Articles with "profibrotic phenotype" as a keyword



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IL-11 Is Elevated and Drives the Profibrotic Phenotype Transition of Orbital Fibroblasts in Thyroid-Associated Ophthalmopathy

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Published in 2022 at "Frontiers in Endocrinology"

DOI: 10.3389/fendo.2022.846106

Abstract: Orbital fibrosis is a hallmark of tissue remodeling in thyroid-associated ophthalmopathy (TAO). Previous studies have shown that interleukin (IL)-11 plays a pivotal profibrotic role in various inflammatory and autoimmune diseases. However, the expression pattern of… read more here.

Keywords: profibrotic phenotype; orbital connective; associated ophthalmopathy; orbital fibroblasts ... See more keywords