Articles with "profile riociguat" as a keyword



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Clinical Pharmacokinetic and Pharmacodynamic Profile of Riociguat

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Published in 2017 at "Clinical Pharmacokinetics"

DOI: 10.1007/s40262-017-0604-7

Abstract: Oral riociguat is a soluble guanylate cyclase (sGC) stimulator that targets the nitric oxide (NO)–sGC–cyclic guanosine monophosphate pathway with a dual mode of action: directly by stimulating sGC, and indirectly by increasing the sensitivity of… read more here.

Keywords: pharmacodynamic profile; profile riociguat; sgc; pharmacokinetic pharmacodynamic ... See more keywords