Articles with "profile vivo" as a keyword



Pharmacokinetic profile and in vivo anticancer efficacy of anagrelide administered subcutaneously in rodents

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Published in 2025 at "Drug Delivery"

DOI: 10.1080/10717544.2025.2463433

Abstract: Abstract Anagrelide (ANA) is a phosphodiesterase 3A (PDE3A) inhibitor, commonly prescribed for essential thrombocythemia. It also functions as a molecular glue, inducing complex formation between PDE3A and Schlafen 12. This association either triggers apoptosis or… read more here.

Keywords: profile vivo; vivo anticancer; efficacy; tumor ... See more keywords