Evaluation of the profiles of CB1 cannabinoid receptor signalling bias using joint kinetic modelling
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DOI: 10.1111/bph.15066
Abstract: Biased agonism describes the ability of ligands to differentially regulate multiple signalling pathways when coupled to a single receptor. Signalling is affected by rapid agonist‐induced receptor internalisation. Hence, the conventional use of equilibrium models may… read more here.
Keywords: receptor signalling; evaluation profiles; profiles cb1; cb1 cannabinoid ... See more keywords