Metabolic profiles of pomalidomide in human plasma simulated with pharmacokinetic data in control and humanized-liver mice
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DOI: 10.1080/00498254.2016.1247218
Abstract: Abstract 1. Pomalidomide has been shown to be potentially teratogenic in thalidomide-sensitive animal species such as rabbits. Screening for thalidomide analogs devoid of teratogenicity/toxicity – attributable to metabolites formed by cytochrome P450 enzymes – but having… read more here.
Keywords: profiles pomalidomide; human plasma; liver mice; humanized liver ... See more keywords