Computational modeling highlights the role of the disordered Formin Homology 1 domain in profilin‐actin transfer
Sign Up to like & getrecommendations! Published in 2018 at "FEBS Letters"
DOI: 10.1002/1873-3468.13088
Abstract: Formins accelerate actin polymerization, assumed to occur through flexible Formin Homology 1 (FH1) domain‐mediated transfer of profilin‐actin to the barbed end. To study FH1 properties and address sequence effects, including varying length/distribution of profilin‐binding proline‐rich… read more here.
Keywords: profilin; formin homology; profilin actin; transfer ... See more keywords
A unique profilin-actin interface is important for malaria parasite motility
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DOI: 10.1371/journal.ppat.1006412
Abstract: Profilin is an actin monomer binding protein that provides ATP-actin for incorporation into actin filaments. In contrast to higher eukaryotic cells with their large filamentous actin structures, apicomplexan parasites typically contain only short and highly… read more here.
Keywords: malaria parasite; profilin; actin; profilin actin ... See more keywords