Comparison of Different Competitive Proteome Profiling Approaches in Target Identification of Covalent Inhibitors
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DOI: 10.1002/cbic.202200389
Abstract: Competitive proteome profiling is a powerful approach for the identification of targets of small molecules. This approach usually employs an inhibitor‐derived probe or a cysteine‐reactive probe such as an IA‐alkyne in a comparison between inhibitor‐treated… read more here.
Keywords: comparison different; profiling approaches; competitive proteome; proteome profiling ... See more keywords
Insights Into the Biogenesis and Emerging Functions of Lipid Droplets From Unbiased Molecular Profiling Approaches
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2022.901321
Abstract: Lipid droplets (LDs) are spherical, single sheet phospholipid-bound organelles that store neutral lipids in all eukaryotes and some prokaryotes. Initially conceived as relatively inert depots for energy and lipid precursors, these highly dynamic structures play… read more here.
Keywords: profiling approaches; lipid droplets; biogenesis emerging; insights biogenesis ... See more keywords