Enzymatic Approaches for Profiling Cytosine Methylation and Hydroxymethylation.
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DOI: 10.1016/j.molmet.2021.101314
Abstract: BACKGROUND In mammalian genomes, modifications to cytosine bases, particularly in cytosine-guanine (CpG) dinucleotide contexts, play a major role in shaping the epigenome. The canonical epigenetic mark is 5-methylcytosine (5mC), but oxidized versions of 5mC including… read more here.
Keywords: methylation; dna; enzymatic approaches; profiling cytosine ... See more keywords