Genetic alterations, RNA expression profiling and DNA methylation of HMGB1 in malignancies
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Cellular and Molecular Medicine"
DOI: 10.1111/jcmm.17454
Abstract: The high mobility group box 1 (HMGB1) is a potential biomarker and therapeutic target in various human diseases. However, a systematic, comprehensive pan‐cancer analysis of HMGB1 in human cancers remains to be reported. This study… read more here.
Keywords: profiling dna; rna expression; dna methylation; expression ... See more keywords
Profiling DNA break sites and transcriptional changes in response to contextual fear learning
Sign Up to like & getrecommendations! Published in 2021 at "PLoS ONE"
DOI: 10.1371/journal.pone.0249691
Abstract: Neuronal activity generates DNA double-strand breaks (DSBs) at specific loci in vitro and this facilitates the rapid transcriptional induction of early response genes (ERGs). Physiological neuronal activity, including exposure of mice to learning behaviors, also… read more here.
Keywords: transcriptional changes; profiling dna; response; dna break ... See more keywords