Articles with "profiling glioblastoma" as a keyword



TurboID‐Mediated Profiling of Glioblastoma‐Derived Extracellular Vesicle Cargo Proteins

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Published in 2025 at "Journal of Extracellular Vesicles"

DOI: 10.1002/jev2.70158

Abstract: ABSTRACT Glioblastoma (GBM), the most aggressive primary brain tumour in adults, presents significant challenges due to its universal recurrence and limited survival rates. A key driver of GBM progression is the subpopulation of brain tumour‐initiating… read more here.

Keywords: cargo; turboid mediated; profiling glioblastoma; glioblastoma ... See more keywords

IMMU-67. On-Treatment Spatiotemporal Profiling of Glioblastoma During Oncolytic ImmunoTherapy

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Published in 2025 at "Neuro-Oncology"

DOI: 10.1093/neuonc/noaf201.0865

Abstract: Glioblastoma (GBM) is the most common and deadliest primary brain tumor, with no effective therapies and a longstanding record of failed phase 3 clinical trials—often without mechanistic insight into why promising approaches fall short. To… read more here.

Keywords: treatment; profiling glioblastoma; glioblastoma; immu treatment ... See more keywords

Kinomic profiling of glioblastoma cells reveals PLCG1 as a target in restricted glucose

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Published in 2018 at "Biomarker Research"

DOI: 10.1186/s40364-018-0136-9

Abstract: BackgroundFor glioblastoma (GBM) treatments to be effective in vivo, understanding the effects of the tumor microenvironment is imperative. In traditional cell culture conditions, glucose concentrations do not model physiologic levels, nor the diminished concentrations found… read more here.

Keywords: glioblastoma cells; profiling glioblastoma; restricted glucose; kinomic profiling ... See more keywords

Bioenergetic Profiling in Glioblastoma Multiforme Patients with Different Clinical Outcomes

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Published in 2023 at "Metabolites"

DOI: 10.3390/metabo13030362

Abstract: The accumulation of cell biomass is associated with dramatically increased bioenergetic and biosynthetic demand. Metabolic reprogramming, once thought as an epiphenomenon, currently relates to disease progression, also in response to extracellular fate-decisive signals. Glioblastoma multiforme… read more here.

Keywords: profiling glioblastoma; multiforme patients; bioenergetic profiling; patients different ... See more keywords