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Published in 2025 at "Journal of Extracellular Vesicles"
DOI: 10.1002/jev2.70158
Abstract: ABSTRACT Glioblastoma (GBM), the most aggressive primary brain tumour in adults, presents significant challenges due to its universal recurrence and limited survival rates. A key driver of GBM progression is the subpopulation of brain tumour‐initiating…
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Keywords:
cargo;
turboid mediated;
profiling glioblastoma;
glioblastoma ... See more keywords
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Published in 2025 at "Neuro-Oncology"
DOI: 10.1093/neuonc/noaf201.0865
Abstract: Glioblastoma (GBM) is the most common and deadliest primary brain tumor, with no effective therapies and a longstanding record of failed phase 3 clinical trials—often without mechanistic insight into why promising approaches fall short. To…
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Keywords:
treatment;
profiling glioblastoma;
glioblastoma;
immu treatment ... See more keywords
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Published in 2018 at "Biomarker Research"
DOI: 10.1186/s40364-018-0136-9
Abstract: BackgroundFor glioblastoma (GBM) treatments to be effective in vivo, understanding the effects of the tumor microenvironment is imperative. In traditional cell culture conditions, glucose concentrations do not model physiologic levels, nor the diminished concentrations found…
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Keywords:
glioblastoma cells;
profiling glioblastoma;
restricted glucose;
kinomic profiling ... See more keywords
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Published in 2023 at "Metabolites"
DOI: 10.3390/metabo13030362
Abstract: The accumulation of cell biomass is associated with dramatically increased bioenergetic and biosynthetic demand. Metabolic reprogramming, once thought as an epiphenomenon, currently relates to disease progression, also in response to extracellular fate-decisive signals. Glioblastoma multiforme…
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Keywords:
profiling glioblastoma;
multiforme patients;
bioenergetic profiling;
patients different ... See more keywords