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   Articles with "profiling identifies" as a keyword



Single-Cell Profiling Identifies Key Pathways Expressed by iPSCs Cultured in Different Commercial Media

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recommendations! Published in 2018 at "iScience"

DOI: 10.1016/j.isci.2018.08.016

Abstract: Summary We assessed the pluripotency of human induced pluripotent stem cells (iPSCs) maintained on an automated platform using StemFlex and TeSR-E8 media. Analysis of transcriptome of single cells revealed similar expression of core pluripotency genes,… read more here.

Keywords: single cell; profiling identifies; key pathways; identifies key ... See more keywords

Endogenous interaction profiling identifies DDX5 as an oncogenic coactivator of transcription factor Fra-1

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recommendations! Published in 2019 at "Oncogene"

DOI: 10.1038/s41388-019-0824-4

Abstract: Fra-1, a member of the activator protein 1 (AP-1) family, is overexpressed in triple-negative breast cancer (TNBC) and plays crucial roles in tumor growth. Here we report the identification of 118 proteins interacting with endogenous… read more here.

Keywords: interaction profiling; identifies ddx5; profiling identifies; ddx5 oncogenic ... See more keywords

Global ubiquitinome profiling identifies NEDD4 as a regulator of Profilin 1 and actin remodelling in neural crest cells.

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recommendations! Published in 2022 at "Nature communications"

DOI: 10.1038/s41467-022-29660-3

Abstract: The ubiquitin ligase NEDD4 promotes neural crest cell (NCC) survival and stem-cell like properties to regulate craniofacial and peripheral nervous system development. However, how ubiquitination and NEDD4 control NCC development remains unknown. Here we combine… read more here.

Keywords: ubiquitinome profiling; profilin; global ubiquitinome; crest ... See more keywords

Longitudinal expression profiling identifies a poor risk subset of patients with ABC-type diffuse large B-cell lymphoma

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recommendations! Published in 2022 at "Blood Advances"

DOI: 10.1182/bloodadvances.2022007536

Abstract: Key Points • Cell of origin is stable between diagnosis and relapse.• A 30-gene panel of relapse-associated genes was able to stratify ABC patient survival at diagnosis. read more here.

Keywords: poor risk; identifies poor; profiling identifies; risk subset ... See more keywords

Sinonasal DLBCL: molecular profiling identifies subtypes with distinctive prognosis and targetable genetic features

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recommendations! Published in 2024 at "Blood Advances"

DOI: 10.1182/bloodadvances.2023011517

Abstract: Key Points • ABC and GCB subtype sinonasal DLBCL are geno- and phenotypically distinct entities, exhibiting a contrasting disease course and prognosis.• ABC subtype sinonasal DLBCL is part of a superordinate family of MCD lymphomas,… read more here.

Keywords: sinonasal dlbcl; molecular profiling; profiling identifies; dlbcl molecular ... See more keywords

MicroRNA profiling identifies a novel compound with antidepressant properties

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recommendations! Published in 2019 at "PLoS ONE"

DOI: 10.1371/journal.pone.0221163

Abstract: Patients with traumatic brain injury (TBI) are frequently diagnosed with depression. Together, these two leading causes of death and disability significantly contribute to the global burden of healthcare costs. However, there are no drug treatments… read more here.

Keywords: antidepressant properties; depression; profiling identifies; antidepressant ... See more keywords

Genome-Wide Integrative Transcriptional Profiling Identifies Age-Associated Signatures in Dogs

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recommendations! Published in 2023 at "Genes"

DOI: 10.3390/genes14061131

Abstract: Mammals experience similar stages of embryonic development, birth, infancy, youth, adolescence, maturity, and senescence. While embryonic developmental processes have been extensively researched, many molecular mechanisms regulating the different life stages after birth, such as aging,… read more here.

Keywords: genome wide; wide integrative; transcriptional profiling; age ... See more keywords

Proteomic Profiling Identifies MARCO in Extracellular Vesicles, as a Potential Biomarker for Leishmaniasis in HIV Co-Infection

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recommendations! Published in 2025 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms26125691

Abstract: Leishmania is an intracellular protozoan parasite that causes leishmaniasis, a disease prevalent in 97 countries. Co-infection with HIV increases susceptibility to visceral leishmaniasis (VL), accelerating HIV’s progression to AIDS. Managing VL in HIV-infected individuals is… read more here.

Keywords: extracellular vesicles; hiv; profiling identifies; leishmaniasis ... See more keywords

LncRNA microarray profiling identifies novel circulating lncRNAs in hidradenitis suppurativa

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recommendations! Published in 2024 at "Molecular Medicine Reports"

DOI: 10.3892/mmr.2024.13236

Abstract: Long noncoding RNAs (lncRNAs) have been demonstrated to be involved in biological processes, both physiological and pathological, including cancer, cardiovascular diseases, multiple sclerosis, autoimmune hepatitis and types I and II diabetes. LncRNAs are also known… read more here.

Keywords: microarray profiling; lncrna microarray; profiling identifies; identifies novel ... See more keywords