Articles with "profiling impact" as a keyword



Profiling the Impact of mGlu7/Elfn1 Protein Interactions on the Pharmacology of mGlu7 Allosteric Modulators

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Published in 2025 at "ACS Chemical Neuroscience"

DOI: 10.1021/acschemneuro.5c00174

Abstract: The group III metabotropic glutamate receptors (mGlu receptors) are predominantly expressed presynaptically throughout the central nervous system (CNS) where they regulate the release of glutamate and GABA. These receptors have recently been shown to be… read more here.

Keywords: allosteric modulators; mglu7; profiling impact; pharmacology ... See more keywords