Immune profiling of NF1-associated tumors reveals histologic subtype distinctions and heterogeneity: Implications for immunotherapy.
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DOI: 10.18632/oncotarget.18301
Abstract: Successful treatment of neurofibromatosis type 1 (NF1)-associated tumors poses a significant clinical challenge. While the primary underlying genetic defect driving RAS signaling is well described, recent evidence suggests immune dysfunction contributes to tumor pathogenesis and… read more here.
Keywords: associated tumors; heterogeneity; profiling nf1; nf1 associated ... See more keywords