Ex vivo immune profiling in patient blood enables quantification of innate immune effector functions
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DOI: 10.1038/s41598-021-91362-5
Abstract: The assessment of a patient’s immune function is critical in many clinical situations. In complex clinical immune dysfunction like sepsis, which results from a loss of immune homeostasis due to microbial infection, a plethora of… read more here.
Keywords: profiling patient; vivo immune; blood; quantification ... See more keywords
Transcriptional Profiling of a Patient-Matched Cohort of Glioblastoma (IDH-Wildtype) for Therapeutic Target and Repurposing Drug Identification
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DOI: 10.3390/biomedicines11041219
Abstract: Glioblastoma (GBM) is the most prevalent and aggressive adult brain tumor. Despite multi-modal therapies, GBM recurs, and patients have poor survival (~14 months). Resistance to therapy may originate from a subpopulation of tumor cells identified… read more here.
Keywords: glioblastoma; transcriptional profiling; profiling patient; target ... See more keywords