Deep immune profiling of patients treated with lenalidomide and dexamethasone with or without daratumumab
Sign Up to like & getrecommendations! Published in 2020 at "Leukemia"
DOI: 10.1038/s41375-020-0855-4
Abstract: CD38-targeted antibody, daratumumab, is approved for the treatment of multiple myeloma (MM). Phase 1/2 studies GEN501/SIRIUS revealed a novel immunomodulatory mechanism of action (MOA) of daratumumab that enhanced the immune response, reducing natural killer (NK)… read more here.
Keywords: profiling patients; deep immune; dexamethasone; immune profiling ... See more keywords
Risk profiling of patients with relapsed/refractory diffuse large B-cell lymphoma by measuring circulating tumor DNA
Sign Up to like & getrecommendations! Published in 2022 at "Blood Advances"
DOI: 10.1182/bloodadvances.2021006415
Abstract: Key Points The level of baseline ctDNA correlated with PFS and OS in patients with R/R DLBCL receiving pola plus BR or BR alone. Patients with a CR had a significantly greater median decrease in… read more here.
Keywords: refractory diffuse; relapsed refractory; diffuse large; profiling patients ... See more keywords
Tumor/normal genomic profiling in patients with metastatic solid tumors identifies pathogenic germline variants of therapeutic importance.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2020.38.15_suppl.1501
Abstract: 1501Background: Tumor molecular profiling via next-generation sequencing (NGS) is routinely utilized to direct patients toward clinical trials of targeted therapeutics. NGS testing of paired tumor/... read more here.
Keywords: profiling; normal genomic; tumor normal; genomic profiling ... See more keywords
Plasma protein profiling in patients undergoing coronary artery bypass grafting surgery and clinical significance
Sign Up to like & getrecommendations! Published in 2017 at "Oncotarget"
DOI: 10.18632/oncotarget.16366
Abstract: This study was designed to identify the protein profiling in patients with triple vessel coronary artery disease (CAD) undergoing CABG, in order to detect CAD-related differential proteins in these patients. CABG patients with triple vessel… read more here.
Keywords: protein; disease; coronary artery; protein profiling ... See more keywords