Metabolite Profiling and Reaction Phenotyping for the in vitro Assessment of the Bioactivation of Bromfenac.
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DOI: 10.1021/acs.chemrestox.9b00268
Abstract: Bromfenac is a non-steroidal anti-inflammatory drug that was approved and subsequently withdrawn from the market due to reported cases of acute hepatotoxicity. Recently, in vitro studies have revealed that bromfenac requires UDPGA and alamethicin supplemented… read more here.
Keywords: profiling reaction; bioactivation; metabolite profiling; bromfenac ... See more keywords