Articles with "progenitor" as a keyword



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Association Between Change in Circulating Progenitor Cells During Exercise Stress and Risk of Adverse Cardiovascular Events in Patients With Coronary Artery Disease.

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Published in 2019 at "JAMA cardiology"

DOI: 10.1001/jamacardio.2019.4528

Abstract: Importance Stem and progenitor cells mobilize from the bone marrow in response to myocardial ischemia. However, the association between the change in circulating progenitor cell (CPC) counts and disease prognosis among patients with ischemia is… read more here.

Keywords: change; stress; ischemia; progenitor ... See more keywords
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Matrix‐Embedded Endothelial Cells Attain a Progenitor‐Like Phenotype

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Published in 2017 at "Advanced Biosystems"

DOI: 10.1002/adbi.201700057

Abstract: Culture of endothelial cells (ECs) embedded in 3D scaffolds of denatured collagen has shown tremendous therapeutic potential in clinical trials of tissue repair. It is postulated that these matrix‐embedded ECs (MEECs) attain a differential phenotype… read more here.

Keywords: phenotype; matrix embedded; expression; endothelial cells ... See more keywords
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A Bioprinted Cardiac Patch Composed of Cardiac‐Specific Extracellular Matrix and Progenitor Cells for Heart Repair

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Published in 2018 at "Advanced Healthcare Materials"

DOI: 10.1002/adhm.201800672

Abstract: Congenital heart defects are present in 8 of 1000 newborns and palliative surgical therapy has increased survival. Despite improved outcomes, many children develop reduced cardiac function and heart failure requiring transplantation. Human cardiac progenitor cell… read more here.

Keywords: heart; extracellular matrix; progenitor; cecm ... See more keywords
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Ablation of cdk4 and cdk6 affects proliferation of basal progenitor cells in the developing dorsal and ventral forebrain

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Published in 2018 at "Developmental Neurobiology"

DOI: 10.1002/dneu.22588

Abstract: Little is known about the molecular players driving proliferation of neural progenitor cells (NPCs) during embryonic mouse development. Here, we demonstrate that proliferation of NPCs in the developing forebrain depends on a particular combination of… read more here.

Keywords: cdk4 cdk6; progenitor cells; proliferation; progenitor ... See more keywords
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TGF‐β pro‐oligodendrogenic effects on adult SVZ progenitor cultures and its interaction with the Notch signaling pathway

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Published in 2018 at "Glia"

DOI: 10.1002/glia.23253

Abstract: Adult neural progenitor cells (NPCs) are capable of differentiating into neurons, astrocytes, and oligodendrocytes throughout life. Notch and transforming growth factor β1 (TGF‐β) signaling pathways play critical roles in controlling these cell fate decisions. TGF‐β… read more here.

Keywords: cell; interaction notch; svz; progenitor ... See more keywords
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Astrocyte progenitor transplantation promotes regeneration of bulbospinal respiratory axons, recovery of diaphragm function, and a reduced macrophage response following cervical spinal cord injury

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Published in 2019 at "Glia"

DOI: 10.1002/glia.23555

Abstract: Stem/progenitor cell transplantation delivery of astrocytes is a potentially powerful strategy for spinal cord injury (SCI). Axon extension into SCI lesions that occur spontaneously or in response to experimental manipulations is often observed along endogenous… read more here.

Keywords: response; diaphragm function; transplantation; progenitor ... See more keywords
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ErbB receptor signaling directly controls oligodendrocyte progenitor cell transformation and spontaneous remyelination after spinal cord injury

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Published in 2019 at "Glia"

DOI: 10.1002/glia.23586

Abstract: We recently discovered a novel role for neuregulin‐1 (Nrg1) signaling in mediating spontaneous regenerative processes and functional repair after spinal cord injury (SCI). We revealed that Nrg1 is the molecular signal responsible for spontaneous functional… read more here.

Keywords: remyelination; transformation; erbb; receptor ... See more keywords
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New insights into the cellular makeup and progenitor potential of palatal connective tissues

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Published in 2017 at "Microscopy Research and Technique"

DOI: 10.1002/jemt.22925

Abstract: The present study investigated the regenerative potential of connective tissues harvested from two palatal areas widely used as donor sites for muco‐gingival surgical approaches. Connective tissue grafts (CTGs) were obtained by de‐epithelialisation of a free… read more here.

Keywords: cell lines; insights cellular; connective tissues; new insights ... See more keywords
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Oligodendrocyte progenitor proliferation is disinhibited following traumatic brain injury in leukemia inhibitory factor heterozygous mice.

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Published in 2021 at "Journal of neuroscience research"

DOI: 10.1002/jnr.24984

Abstract: Traumatic brain injury (TBI) is a significant problem that affects over 800,000 children each year. As cell proliferation is disturbed by injury and required for normal brain development, we investigated how a pediatric closed head… read more here.

Keywords: cell proliferation; lif; proliferation; mice ... See more keywords
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Proteomic analysis of the IPF mesenchymal progenitor cell nuclear proteome identifies abnormalities in key nodal proteins that underlie their fibrogenic phenotype

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Published in 2022 at "Proteomics"

DOI: 10.1002/pmic.202200018

Abstract: IPF is a progressive fibrotic lung disease whose pathogenesis remains incompletely understood. We have previously discovered pathologic mesenchymal progenitor cells (MPCs) in the lungs of IPF patients. IPF MPCs display a distinct transcriptome and create… read more here.

Keywords: ipf; phenotype; progenitor; mesenchymal progenitor ... See more keywords
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Sox2 Expression Marks Castration‐Resistant Progenitor Cells in the Adult Murine Prostate

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Published in 2019 at "STEM CELLS"

DOI: 10.1002/stem.2987

Abstract: Identification of defined epithelial cell populations with progenitor properties is critical for understanding prostatic development and disease. Here, we demonstrate that Sox2 expression is enriched in the epithelial cells of the proximal prostate adjacent to… read more here.

Keywords: prostate; sox2 expression; castration; sox2 ... See more keywords