Microtissue Geometry and Cell-Generated Forces Drive Patterning of Liver Progenitor Cell Differentiation in 3D.
Sign Up to like & getrecommendations! Published in 2021 at "Advanced healthcare materials"
DOI: 10.1002/adhm.202100223
Abstract: 3D microenvironments provide a unique opportunity to investigate the impact of intrinsic mechanical signaling on progenitor cell differentiation. Using a hydrogel-based microwell platform, arrays of 3D, multicellular microtissues in constrained geometries, including toroids and cylinders… read more here.
Keywords: progenitor cell; geometry; cell; cell differentiation ... See more keywords
Irisin promotes cardiac progenitor cell‐induced myocardial repair and functional improvement in infarcted heart
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.27037
Abstract: Irisin, a newly identified hormone and cardiokine, is critical for modulating body metabolism. New evidence indicates that irisin protects the heart against myocardial ischemic injury. However, whether irisin enhances cardiac progenitor cell (CPC)‐induced cardiac repair… read more here.
Keywords: functional improvement; progenitor cell; cardiac progenitor; irisin ... See more keywords
Cardiac Progenitor Cell Extraction from Human Auricles.
Sign Up to like & getrecommendations! Published in 2017 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-6756-8_11
Abstract: For many years, myocardial tissue has been considered terminally differentiated and, thus, incapable of regenerating. Recent studies have shown, instead, that cardiomyocytes, at least in part, are slowly substituted by new cells originating by precursor… read more here.
Keywords: cell extraction; extraction human; progenitor cell; cardiac progenitor ... See more keywords
Cardiac Progenitor Cell-Derived Extracellular Vesicles: a Rising Star for Cardiac Repair and Regeneration
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cardiovascular Translational Research"
DOI: 10.1007/s12265-018-9862-5
Abstract: Cardiovascular diseases represent a significant cause of death and disability worldwide [1]. Myocardial infarction (MI), among other cardiovascular diseases, causes massive cardiomyocyte loss and scar formation in place of dead myocardial tissues, thus leading to… read more here.
Keywords: extracellular vesicles; progenitor cell; cardiac progenitor; progenitor ... See more keywords
Progenitor cell-based treatment of glial disease.
Sign Up to like & getrecommendations! Published in 2017 at "Progress in brain research"
DOI: 10.1016/bs.pbr.2017.02.010
Abstract: Diseases of glia, including astrocytes and oligodendrocytes, are among the most prevalent and disabling, yet least appreciated, conditions in neurology. In recent years, it has become clear that besides the overtly glial disorders of oligodendrocyte… read more here.
Keywords: cell based; progenitor cell; treatment; disease ... See more keywords
Endothelial progenitor cell secretome delivered by novel polymeric nanoparticles in ischemic hindlimb
Sign Up to like & getrecommendations! Published in 2018 at "International Journal of Pharmaceutics"
DOI: 10.1016/j.ijpharm.2018.03.015
Abstract: &NA; Endothelial progenitor cells (EPCs) contribute to ischemic tissue repair by paracrine secretion up‐regulated by hypoxia. In this study we use novel nanoparticles (NPs) as carriers for a controlled release of EPC secretome (CM) to… read more here.
Keywords: progenitor cell; endothelial progenitor; ischemic hindlimb; hypoxic epc ... See more keywords
Keratinocyte growth factor (KGF) induces stem/progenitor cell growth in middle ear mucosa.
Sign Up to like & getrecommendations! Published in 2019 at "International journal of pediatric otorhinolaryngology"
DOI: 10.1016/j.ijporl.2019.109699
Abstract: OBJECTIVE The middle ear epithelium is derived from the neural crest and endoderm, which line distinct regions of the middle ear cavity. In this study, we investigated the localization of stem/progenitor cells in the middle… read more here.
Keywords: cell; progenitor cell; stem progenitor; middle ear ... See more keywords
The progenitor cell dilemma: Cellular and functional heterogeneity in assistance or escalation of liver injury.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of hepatology"
DOI: 10.1016/j.jhep.2016.10.033
Abstract: Liver progenitor cells (LPCs) are quiescent cells that are activated during liver injury and thought to give rise to hepatocytes and cholangiocytes in order to support liver regeneration and tissue restitution. While hepatocytes are capable… read more here.
Keywords: liver injury; progenitor; regeneration; progenitor cell ... See more keywords
Histone 2B-GFP Label-Retaining Prostate Luminal Cells Possess Progenitor Cell Properties and Are Intrinsically Resistant to Castration
Sign Up to like & getrecommendations! Published in 2018 at "Stem Cell Reports"
DOI: 10.1016/j.stemcr.2017.11.016
Abstract: Summary The existence of slow-cycling luminal cells in the prostate has been suggested, but their identity and functional properties remain unknown. Using a bigenic mouse model to earmark, isolate, and characterize the quiescent stem-like cells,… read more here.
Keywords: luminal cells; progenitor cell; label retaining; castration ... See more keywords
Hematopoietic stem and progenitor cell signaling in the niche
Sign Up to like & getrecommendations! Published in 2020 at "Leukemia"
DOI: 10.1038/s41375-020-01062-8
Abstract: Hematopoietic stem and progenitor cells (HSPCs) are responsible for lifelong maintenance of hematopoiesis through self-renewal and differentiation into mature blood cell lineages. Traditional models hold that HSPCs guard homeostatic function and adapt to regenerative demand… read more here.
Keywords: stem; progenitor cell; stem progenitor; hematopoietic stem ... See more keywords
Hematopoietic stem and progenitor cell proliferation and differentiation requires the trithorax protein Ash2l
Sign Up to like & getrecommendations! Published in 2019 at "Scientific Reports"
DOI: 10.1038/s41598-019-44720-3
Abstract: Post-translational modifications of core histones participate in controlling the expression of genes. Methylation of lysine 4 of histone H3 (H3K4), together with acetylation of H3K27, is closely associated with open chromatin and gene transcription. H3K4… read more here.
Keywords: stem; progenitor cell; stem progenitor; hematopoietic stem ... See more keywords