TWEAK Signaling-Induced ID1 Expression Drives Malignant Transformation of Hepatic Progenitor Cells During Hepatocarcinogenesis.
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DOI: 10.1002/advs.202300350
Abstract: The malignant transformation of hepatic progenitor cells (HPCs) in the inflammatory microenvironment is the root cause of hepatocarcinogenesis. However, the potential molecular mechanisms are still elusive. The HPCs subgroup is identified by single-cell RNA (scRNA)… read more here.
Keywords: hepatic progenitor; expression; transformation hepatic; progenitor cells ... See more keywords
Levels of circulating endothelial progenitor cells inversely correlate with manic and positive symptom severity in patients with bipolar disorder
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DOI: 10.1002/brb3.2570
Abstract: Patients with bipolar disorder (BPD) are at high risk of cardiovascular diseases (CVDs) that are attributed to endothelial dysfunction. Circulating endothelial progenitor cells (cEPCs) are proposed as indicators of endothelial dysfunction. This study examined the… read more here.
Keywords: endothelial progenitor; circulating endothelial; patients bipolar; bipolar disorder ... See more keywords
Functional damage of endothelial progenitor cells is attenuated by 14‐3‐3‐n through inhibition of mitochondrial injury and oxidative stress
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DOI: 10.1002/cbin.11529
Abstract: Endothelial progenitor cells (EPCs) are precursor cells of vascular endothelial cells, which are widely involved in the pathological process of cardiovascular diseases. EPCs apoptosis could accelerate the process of cardiovascular diseases. 14‐3‐3‐η protein has been… read more here.
Keywords: progenitor cells; apoptosis; mitochondrial injury; inhibition ... See more keywords
Isolation, Culture, and Differentiation of Mammary Epithelial Stem/Progenitor Cells from Fresh or Ex Vivo Cultured Human Breast Tissue
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DOI: 10.1002/cpcb.65
Abstract: In vivo transplantation is the gold standard method for characterization of stem/progenitor cell self‐renewal, tissue regeneration, and tumorigenesis. The method requires an enriched population of stem cells that represent a small fraction of a given… read more here.
Keywords: progenitor cells; tissue; stem progenitor; stem ... See more keywords
CPHEN‐013: Comprehensive phenotyping of hematopoietic stem and progenitor cells in the human fetal liver
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DOI: 10.1002/cyto.a.24540
Abstract: Hematopoietic stem cells (HSCs) reside at the top of the hematopoietic hierarchy and can give rise to all the mature blood cell types in our body, while at the same time maintaining a pool of… read more here.
Keywords: fetal liver; human fetal; hematopoietic stem; stem ... See more keywords
Bone marrow as a target and accomplice of vascular complications in diabetes
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DOI: 10.1002/dmrr.3240
Abstract: Peripheral vascular complications are common in diabetic patients. While pathogenic mechanisms have received much consideration, only recently regenerative processes captured attention. There is now a consensus that the bone marrow is a source of reparative… read more here.
Keywords: progenitor cells; bone; stem progenitor; vascular complications ... See more keywords
Ablation of cdk4 and cdk6 affects proliferation of basal progenitor cells in the developing dorsal and ventral forebrain
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DOI: 10.1002/dneu.22588
Abstract: Little is known about the molecular players driving proliferation of neural progenitor cells (NPCs) during embryonic mouse development. Here, we demonstrate that proliferation of NPCs in the developing forebrain depends on a particular combination of… read more here.
Keywords: cdk4 cdk6; progenitor cells; proliferation; progenitor ... See more keywords
Transcriptome analysis of the response to thyroid hormone in Xenopus neural stem and progenitor cells
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DOI: 10.1002/dvdy.535
Abstract: The thyroid hormones—thyroxine (T4) and 3,5,3′triiodothyronine (T3)—regulate the development of the central nervous system (CNS) in vertebrates by acting in different cell types. Although several T3 target genes have been identified in the brain, the… read more here.
Keywords: neural stem; progenitor cells; response; stem progenitor ... See more keywords
Glial progenitor cells of the adult human white and grey matter are contextually distinct
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DOI: 10.1002/glia.24291
Abstract: Genomic analyses have revealed heterogeneity among glial progenitor cells (GPCs), but the compartment selectivity of human GPCs (hGPCs) is unclear. Here, we asked if GPCs of human grey and white brain matter are distinct in… read more here.
Keywords: matter; white matter; progenitor cells; glial progenitor ... See more keywords
Differential activity of transcription factor Sox9 in early and adult oligodendroglial progenitor cells.
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DOI: 10.1002/glia.24373
Abstract: The high-mobility-group domain-containing transcription factor Sox9 confers glial competence to neuroepithelial precursors in the developing central nervous system and is an important determinant of astroglial and oligodendroglial specification. In oligodendroglial cells, it remains expressed in… read more here.
Keywords: sox9; adult; factor sox9; transcription factor ... See more keywords
Incomplete Differentiation of Engrafted Bone Marrow Endothelial Progenitor Cells Initiates Hepatic Fibrosis in the Rat
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DOI: 10.1002/hep.30227
Abstract: Normal liver sinusoidal endothelial cells (LSECs) promote quiescence of hepatic stellate cells (HSCs). Prior to fibrosis, LSECs undergo capillarization, which is permissive for HSC activation, the proximate event in hepatic fibrosis. The aims of this… read more here.
Keywords: progenitor cells; fibrosis; marrow endothelial; endothelial progenitor ... See more keywords