Adult Pancreatic Acinar Progenitor-like Populations in Regeneration and Cancer.
Sign Up to like & getrecommendations! Published in 2020 at "Trends in molecular medicine"
DOI: 10.1016/j.molmed.2020.04.003
Abstract: The bulk of the pancreas primarily comprises long-lived acinar cells that are not considered a bona fide source for stem cells. However, certain acinar subpopulations have a repopulating capacity during regeneration, raising the hypothesis as… read more here.
Keywords: acinar; regeneration; like populations; cancer ... See more keywords
Low TCR Binding Strength Results in Increased Progenitor-like CD8+ Tumor-Infiltrating Lymphocytes
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Immunology Research"
DOI: 10.1158/2326-6066.cir-22-0761
Abstract: Transcriptional profiling reveals that tumor-infiltrating lymphocytes (TILs) with low TCR affinity to a tumor-associated antigen exhibit progenitor-like phenotypes and increased quiescence, whereas higher affinity TCR TILs exhibit more cell division and faster progression to T-cell… read more here.
Keywords: low tcr; progenitor like; infiltrating lymphocytes; tumor infiltrating ... See more keywords
Establishment of Functional Liver Spheroids From Human Hepatocyte-Derived Liver Progenitor-Like Cells for Cell Therapy
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Bioengineering and Biotechnology"
DOI: 10.3389/fbioe.2021.738081
Abstract: Globally, about two million people die from liver diseases every year. Liver transplantation is the only reliable therapy for severe end-stage liver disease, however, the shortage of organ donors is a huge limitation. Human hepatocytes… read more here.
Keywords: liver progenitor; like cells; liver; cell therapy ... See more keywords