Progesterone-induced blocking factor (PIBF) influences the expression of membrane progesterone receptors (mPRs) on peripheral CD4+ T lymphocyte cells in normal fertile females
Sign Up to like & getrecommendations! Published in 2021 at "Hormones"
DOI: 10.1007/s42000-021-00291-5
Abstract: Progesterone-induced blocking factor (PIBF) is a protein secreted by lymphocytes exposed to progesterone (P4). P4 and PIBF have immunomodulatory effects on peripheral CD4+ T cells during normal pregnancy. Membrane progesterone receptors (mPRs) may correlate with… read more here.
Keywords: peripheral cd4; pibf; progesterone induced; expression ... See more keywords
The immunolocalization of Galectin-1 and Progesterone-Induced Blocking Factor (PIBF) in equine trophoblast: Possible roles in trophoblast invasion and the immunological protection of pregnancy.
Sign Up to like & getrecommendations! Published in 2019 at "Placenta"
DOI: 10.1016/j.placenta.2019.08.081
Abstract: INTRODUCTION The proteins galectin-1 and Progesterone Induced Blocking Factor (PIBF) are present on human and murine trophoblast and are thought to influence both immunomodulation and trophoblast invasion. In equids, the invasive component of the placenta,… read more here.
Keywords: galectin progesterone; pibf; trophoblast; induced blocking ... See more keywords
Progesterone-induced blocking factor 1 and cytokine profile of follicular fluid of infertile women qualified to in vitro fertilization: The influence on fetus development and pregnancy outcome
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Immunopathology and Pharmacology"
DOI: 10.1177/03946320221111134
Abstract: Introduction: Progesterone is essential for both the initiation and the maintenance of pregnancy. The immunological effects of progesterone are mediated by the progesterone-induced blocking factor (PIBF), which is an immunomodulatory factor with anti-abortive properties. The… read more here.
Keywords: progesterone induced; number; concentration; successful ivf ... See more keywords
Role of mPRĪ± (PAQR7) in progesterone-induced Ca2+ decrease in human vascular smooth muscle cells.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of molecular endocrinology"
DOI: 10.1530/jme-19-0019
Abstract: We have shown progesterone exerts a direct action on vascular smooth muscle cells (VSMCs) to induce relaxation through activation of membrane progesterone receptor alpha (mPRĪ±)-dependent signaling pathways, but information on downstream events is lacking. Progesterone-induced… read more here.
Keywords: mpr; vascular smooth; progesterone; calcium ... See more keywords
Altered Immune Response and Implantation Failure in Progesterone-Induced Blocking Factor-Deficient Mice
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DOI: 10.3389/fimmu.2020.00349
Abstract: Earlier data suggest that progesterone-induced blocking factor (PIBF) is involved in implantation. The present study therefore aims to investigate the consequences of functional PIBF deficiency during the peri-implantation period. CD1 female mice were injected intraperitoneally… read more here.
Keywords: progesterone induced; anti pibf; pibf treated; mice ... See more keywords
Effects of Estradiol and Progesterone-Induced Intracellular Calcium Fluxes on Toxoplasma gondii Gliding, Microneme Secretion, and Egress
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DOI: 10.3389/fmicb.2018.01266
Abstract: Research has shown that estrogen is present and plays a critical role in vertebrate reproduction and metabolism, but the influence of steroids on Toxoplasma gondii has received less attention. Our data showed that estradiol and… read more here.
Keywords: secretion; estradiol progesterone; progesterone induced; ca2 ... See more keywords