Liquiritin, as a Natural Inhibitor of AKR1C1, Could Interfere With the Progesterone Metabolism
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Physiology"
DOI: 10.3389/fphys.2019.00833
Abstract: Low progesterone level is always linked with pre-term birth. Therefore, maintaining of progesterone level is vital during pregnancy. Aldo-keto reductase family one member C1 (AKR1C1) catalyzes the reduction of progesterone to its inactive form of… read more here.
Keywords: inhibitor akr1c1; akr1c1; progesterone metabolism; progesterone ... See more keywords
Progesterone Metabolism by Human and Rat Hepatic and Intestinal Tissue
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DOI: 10.3390/pharmaceutics13101707
Abstract: Following oral administration, the bioavailability of progesterone is low and highly variable. As a result, no clinically relevant, natural progesterone oral formulation is available. After oral delivery, first-pass metabolism initially occurs in the intestines; however,… read more here.
Keywords: metabolism human; metabolism; progesterone metabolism; human rat ... See more keywords