Genomic analysis of 5-methylcytosine-related molecular subtypes reveals the characterisation of prognosis and immunotherapy in lung squamous cell carcinoma.
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DOI: 10.1080/14737159.2022.2131396
Abstract: BACKGROUND Methylation of cytosine residues resulting in 5-methylcytosine (5-mC) is an important epigenetic modification associated with tumorigenesis. The present study explored the relationship between methylation, prognosis, and immunotherapy of patients suffering from lung squamous cell… read more here.
Keywords: prognosis; immunotherapy; prognosis immunotherapy; squamous cell ... See more keywords
Molecular Characteristics and the Effect of KRAS Mutation on the Prognosis of Immunotherapy in Non-Small Cell Lung Cancer in Xinjiang, China
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DOI: 10.2147/ott.s381825
Abstract: Purpose Non-small cell lung cancer (NSCLC) is a malignant tumor with high mortality. The Kirsten rat sarcoma vial oncogene (KRAS) gene can affect patient prognosis. In this study, we aim to explore the impact of… read more here.
Keywords: kras mutation; mutation; prognosis immunotherapy; cancer ... See more keywords
Comprehensive Characterization of Pyroptosis Patterns with Implications in Prognosis and Immunotherapy in Low-Grade Gliomas
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DOI: 10.3389/fgene.2021.763807
Abstract: Background: Due to high heterogeneity and mortality of low-grade gliomas (LGGs), it is of great significance to find biomarkers for prognosis and immunotherapy. Pyroptosis is emerging as an attractive target in cancer research for its… read more here.
Keywords: pyroptosis patterns; grade gliomas; prognosis immunotherapy; pyroptosis ... See more keywords
Identification of NAD+ Metabolism-Derived Gene Signatures in Ovarian Cancer Prognosis and Immunotherapy
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DOI: 10.3389/fgene.2022.905238
Abstract: Background: Nicotinamide adenine dinucleotide (NAD+) has emerged as a critical regulator of cell signaling and survival pathways, affecting tumor initiation and progression. In this study it was investigated whether circulating NAD+ metabolism-related genes (NMRGs) could… read more here.
Keywords: immunotherapy; nad metabolism; ovarian cancer; prognosis immunotherapy ... See more keywords
A systematic pan-cancer analysis reveals the clinical prognosis and immunotherapy value of C-X3-C motif ligand 1 (CX3CL1)
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DOI: 10.3389/fgene.2023.1183795
Abstract: It is now widely known that C-X3-C motif ligand 1 (CX3CL1) plays an essential part in the process of regulating pro-inflammatory cells migration across a wide range of inflammatory disorders, including a number of malignancies.… read more here.
Keywords: clinical prognosis; prognosis immunotherapy; cancer; cx3cl1 ... See more keywords
Oncogenic signaling pathway-related long non-coding RNAs for predicting prognosis and immunotherapy response in breast cancer
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DOI: 10.3389/fimmu.2022.891175
Abstract: Background The clinical outcomes of breast cancer (BC) are unpredictable due to the high level of heterogeneity and complex immune status of the tumor microenvironment (TME). When set up, multiple long non-coding RNA (lncRNA) signatures… read more here.
Keywords: oncosig; immunotherapy; prognosis immunotherapy; response ... See more keywords
Identification of N7-methylguanosine related signature for prognosis and immunotherapy efficacy prediction in lung adenocarcinoma
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DOI: 10.3389/fmed.2022.962972
Abstract: Background Lung adenocarcinoma (LUAD) is one of the most frequent causes of tumor-related mortality worldwide. Recently, the role of N7-methylguanosine (m7G) in tumors has begun to receive attention, but no investigation on the impact of… read more here.
Keywords: prognosis; signature; prognosis immunotherapy; m7g score ... See more keywords