The prognostic benefit of tumour-infiltrating Natural Killer cells in endometrial cancer is dependent on concurrent overexpression of Human Leucocyte Antigen-E in the tumour microenvironment.
Sign Up to like & getrecommendations! Published in 2017 at "European journal of cancer"
DOI: 10.1016/j.ejca.2017.09.008
Abstract: BACKGROUND Human Leucocyte Antigen- E (HLA-E) has been reported as both a positive and negative prognostic marker in cancer. This apparent discrepancy may be due to opposing actions of HLA-E on tumour-infiltrating immune cells. Therefore,… read more here.
Keywords: cancer; human leucocyte; hla expression; prognostic benefit ... See more keywords
Prognostic benefit of comprehensive genomic profiling in clinical practice remains uncertain.
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DOI: 10.1111/cas.15826
Abstract: The overall survival of patients who received genomically matched therapy was not significantly longer than that of patients receiving treatment only other than genomically matched therapy in the breast invasive ductal carcinoma (A), colorectal adenocarcinoma… read more here.
Keywords: profiling clinical; genomic profiling; benefit comprehensive; prognostic benefit ... See more keywords