Articles with "prognostic genes" as a keyword



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Data mining of immune-related prognostic genes in metastatic melanoma microenvironment

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Published in 2020 at "Bioscience Reports"

DOI: 10.1042/bsr20201704

Abstract: Abstract Skin cutaneous melanoma (SKCM) is one of the most deadly malignancies. Although immunotherapies showed the potential to improve the prognosis for metastatic melanoma patients, only a small group of patients can benefit from it.… read more here.

Keywords: metastatic melanoma; microenvironment; melanoma; prognostic genes ... See more keywords
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Integrated Analysis of Multi-Omics Data to Identify Prognostic Genes for Pancreatic Cancer.

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Published in 2022 at "DNA and cell biology"

DOI: 10.1089/dna.2021.0878

Abstract: Pancreatic cancer (PC) is a common cause of cancer-related deaths. Current research shows that prognostic biomarkers play a key role in the treatment of PC. This study aimed to identify prognostic genes through bioinformatics research.… read more here.

Keywords: cancer; analysis; expression; prognostic genes ... See more keywords
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Improved prediction of breast cancer outcome by identifying heterogeneous biomarkers

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Published in 2017 at "Bioinformatics"

DOI: 10.1093/bioinformatics/btx487

Abstract: Motivation Identification of genes that can be used to predict prognosis in patients with cancer is important in that it can lead to improved therapy, and can also promote our understanding of tumor progression on… read more here.

Keywords: prognostic genes; improved prediction; breast cancer; cancer ... See more keywords
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Exploring autophagy-related prognostic genes of Alzheimer’s disease based on pathway crosstalk analysis

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Published in 2022 at "Bosnian Journal of Basic Medical Sciences"

DOI: 10.17305/bjbms.2021.7019

Abstract: Recent studies have shown that different signaling pathways are involved in the pathogenesis of Alzheimer’s disease (AD), with complex molecular connections existing between these pathways. Autophagy is crucial for the degradation and production of pathogenic… read more here.

Keywords: prognostic genes; alzheimer disease; pathway crosstalk; analysis ... See more keywords
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Development and Validation of a Prognostic Classifier Based on Lipid Metabolism-Related Genes for Breast Cancer

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Published in 2022 at "Journal of Inflammation Research"

DOI: 10.2147/jir.s357144

Abstract: Background The changes of lipid metabolism have been implicated in the development of many tumors, but its role in breast invasive carcinoma (BRCA) remains to be fully established. Here, we attempted to ascertain the prognostic… read more here.

Keywords: metabolism; prognostic genes; metabolism related; lipid metabolism ... See more keywords
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Exploration of prognostic genes and risk signature in breast cancer patients based on RNA binding proteins associated with ferroptosis

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Published in 2023 at "Frontiers in Genetics"

DOI: 10.3389/fgene.2023.1025163

Abstract: Background: Breast cancer (BRCA) is a life-threatening malignancy in women with an unsatisfactory prognosis. The purpose of this study was to explore the prognostic biomarkers and a risk signature based on ferroptosis-related RNA-binding proteins (FR-RBPs).… read more here.

Keywords: prognostic genes; risk; analysis; cancer ... See more keywords
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FCGR2C: An emerging immune gene for predicting sepsis outcome

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Published in 2022 at "Frontiers in Immunology"

DOI: 10.3389/fimmu.2022.1028785

Abstract: Background Sepsis is a life-threatening disease associated with immunosuppression. Immunosuppression could ultimately increase sepsis mortality. This study aimed to identify the prognostic biomarkers related to immunity in sepsis. Methods Public datasets of sepsis downloaded from… read more here.

Keywords: sepsis; gene; prognostic genes; cohort ... See more keywords
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A Systematic Framework for Identifying Prognostic Genes in the Tumor Microenvironment of Colon Cancer

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Published in 2022 at "Frontiers in Oncology"

DOI: 10.3389/fonc.2022.899156

Abstract: As one of the most common cancers of the digestive system, colon cancer is a predominant cause of cancer-related deaths worldwide. To investigate prognostic genes in the tumor microenvironment of colon cancer, we collected 461… read more here.

Keywords: prognostic genes; tumor microenvironment; colon cancer; genes tumor ... See more keywords
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A novel prognostic model based on urea cycle-related gene signature for colorectal cancer

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Published in 2022 at "Frontiers in Surgery"

DOI: 10.3389/fsurg.2022.1027655

Abstract: Background Colorectal cancer (CRC) is the second leading cause of cancer-related deaths in the world. This study aimed to develop a urea cycle (UC)-related gene signature that provides a theoretical foundation for the prognosis and… read more here.

Keywords: related prognostic; prognostic genes; signature; gene signature ... See more keywords
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Cohort size required for prognostic genes analysis of stage II/III esophageal squamous cell carcinoma

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Published in 2023 at "Pathology and Oncology Research"

DOI: 10.3389/pore.2023.1610909

Abstract: Background: Few overlaps between prognostic biomarkers are observed among different independently performed genomic studies of esophageal squamous cell carcinoma (ESCC). One of the reasons for this is the insufficient cohort size. How many cases are… read more here.

Keywords: prognostic genes; genes analysis; cohort size; stage iii ... See more keywords
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Identification of Prognostic Genes in Gliomas Based on Increased Microenvironment Stiffness

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Published in 2022 at "Cancers"

DOI: 10.3390/cancers14153659

Abstract: Simple Summary Glioblastoma multiforme (GBM) is the most aggressive primary brain cancer; less than 50% of patients with GBM survive longer than 15 months. A biomarker for early GBM diagnosis can substantially increase the effectiveness… read more here.

Keywords: prognosis; prognostic genes; stiffness; glioma ... See more keywords