Leukocytosis and neutrophilia as independent prognostic immunological biomarkers for clinical outcome in the CAO/ARO/AIO‐04 randomized phase 3 rectal cancer trial
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DOI: 10.1002/ijc.32274
Abstract: Peripheral blood leukocytosis and neutrophilia reflect cancer inflammation and have been proposed as prognostic immunological biomarkers in various malignancies. However, previous studies were limited by their retrospective nature and small patient numbers. Baseline peripheral blood… read more here.
Keywords: clinical outcome; leukocytosis neutrophilia; cancer; prognostic immunological ... See more keywords
Prognostic and Immunological Significance of FUNDC1 in Hepatocellular Carcinoma: A Study on TCGA Mining
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DOI: 10.1155/2022/8371885
Abstract: Background Hepatocellular carcinoma (HCC) is an inflammation-related malignancy influenced by the immune microenvironment, such as immune tolerance and evasion. HFUN14 domain-with protein 1 (FUNDC1) is a necessary mitochondrial outer membrane protein, functioning as a receptor… read more here.
Keywords: hepatocellular carcinoma; prognostic immunological; fundc1; tumor ... See more keywords
Diagnostic, Prognostic, and Immunological Roles of HELLS in Pan-Cancer: A Bioinformatics Analysis
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DOI: 10.3389/fimmu.2022.870726
Abstract: Background Inappropriate repair of DNA damage drives carcinogenesis. Lymphoid-specific helicase (HELLS) is an important component of the chromatin remodeling complex that helps repair DNA through various mechanisms such as DNA methylation, histone posttranslational modification, and… read more here.
Keywords: role hells; prognostic immunological; hells cancers; diagnostic prognostic ... See more keywords
Integrated profiling uncovers prognostic, immunological, and pharmacogenomic features of ferroptosis in triple-negative breast cancer
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DOI: 10.3389/fimmu.2022.985861
Abstract: Objective Ferroptosis is an iron-dependent type of regulated cell death triggered by the toxic buildup of lipid peroxides on cell membranes. Nonetheless, the implication of ferroptosis in triple‐negative breast cancer (TNBC), which is the most… read more here.
Keywords: breast; ferroptosis triple; triple negative; prognostic immunological ... See more keywords
A pan-cancer analysis of the prognostic and immunological roles of matrix metalloprotease-1 (MMP1) in human tumors
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DOI: 10.3389/fonc.2022.1089550
Abstract: Objective Cancer remains the leading killer of human health worldwide. It has been shown that matrix metalloproteinase-1(MMP1) is related to poor prognosis in cancers such as BRCA, CESC and COAD. However, systematic pan-cancer analysis about… read more here.
Keywords: pan cancer; biology; mmp1; analysis ... See more keywords
Prognostic and Immunological Role of STK38 across Cancers: Friend or Foe?
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DOI: 10.3390/ijms231911590
Abstract: Although STK38 (serine-threonine kinase 38) has been proven to play an important role in cancer initiation and progression based on a series of cell and animal experiments, no systemic assessment of STK38 across human cancers… read more here.
Keywords: stk38 across; stk38; prognostic immunological; cancer ... See more keywords
Prognostic and Immunological Implications of FAM72A in Pan-Cancer and Functional Validations
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DOI: 10.3390/ijms24010375
Abstract: The family with sequence similarity 72 Member A (FAM72A) is overexpressed in several types of cancer. However, its contributions to tumorigenesis remain largely unknown. Based on The Cancer Genome Atlas (TCGA) database, FAM72A was upregulated… read more here.
Keywords: fam72a pan; fam72a; prognostic immunological; implications fam72a ... See more keywords