Prognostic, predictive, and pharmacogenomic assessments of CDX2 refine stratification of colorectal cancer
Sign Up to like & getrecommendations! Published in 2018 at "Molecular Oncology"
DOI: 10.1002/1878-0261.12347
Abstract: We aimed to refine the value of CDX2 as an independent prognostic and predictive biomarker in colorectal cancer (CRC) according to disease stage and chemotherapy sensitivity in preclinical models. CDX2 expression was evaluated in 1045… read more here.
Keywords: chemotherapy; colorectal cancer; prognostic predictive; stage ... See more keywords
Reply to Neutrophil‐to‐lymphocyte ratio as a bladder cancer biomarker: Assessing prognostic and predictive value in SWOG 8710
Sign Up to like & getrecommendations! Published in 2017 at "Cancer"
DOI: 10.1002/cncr.30871
Abstract: In their letter, Dolan and McMillan raise several important points. First, many studies have concluded that the neutrophil-to-lymphocyte ratio (NLR) is a cancer biomarker. Second, the majority of studies analyzed NLR as a dichotomized variable.… read more here.
Keywords: cancer biomarker; ratio; neutrophil lymphocyte; prognostic predictive ... See more keywords
Evaluation of the circulating MicroRNA‐495 and Stat3 as prognostic and predictive biomarkers for lower extremity deep venous thrombosis
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.26633
Abstract: This study aims to elucidate the prognostic and predictive biomarker of miR‐495 and Stat3 in peripheral blood in relation to lower extremity deep venous thrombosis (DVT). Patients with lower limb fractures were assigned into case… read more here.
Keywords: lower extremity; mir 495; stat3; prognostic predictive ... See more keywords
A review of prognostic and predictive biomarkers in breast cancer
Sign Up to like & getrecommendations! Published in 2022 at "Clinical and Experimental Medicine"
DOI: 10.1007/s10238-021-00781-1
Abstract: Breast cancer (BC) is a common cancer all over the world that affects women. BC is one of the leading causes of cancer mortality in women, which today has decreased with the advancement of technology… read more here.
Keywords: cancer; predictive biomarkers; review prognostic; biomarkers breast ... See more keywords
Prognostic and predictive value of circulating tumor cells and CXCR4 expression as biomarkers for a CXCR4 peptide antagonist in combination with carboplatin-etoposide in small cell lung cancer: exploratory analysis of a phase II study
Sign Up to like & getrecommendations! Published in 2017 at "Investigational New Drugs"
DOI: 10.1007/s10637-017-0446-z
Abstract: SummaryBackground Circulating tumor cells (CTCs) and chemokine (C-X-C motif) receptor 4 (CXCR4) expression in CTCs and tumor tissue were evaluated as prognostic or predictive markers of CXCR4 peptide antagonist LY2510924 plus carboplatin-etoposide (CE) versus CE… read more here.
Keywords: cxcr4 expression; prognostic predictive; ctcs; tumor ... See more keywords
Prognostic and predictive impact of MGMT promoter methylation status in high risk grade II glioma
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Neuro-Oncology"
DOI: 10.1007/s11060-022-03955-3
Abstract: MGMT promoter methylation has been associated with favorable prognosis and survival outcomes in patients with glioblastoma and WHO grade III glioma. However, the effects of promoter methylation of MGMT in patients with WHO grade II… read more here.
Keywords: methylation; grade glioma; prognostic predictive; mgmt ... See more keywords
Evolving Tissue and Circulating Biomarkers as Prognostic and Predictive Tools in Colorectal Cancer
Sign Up to like & getrecommendations! Published in 2018 at "Current Colorectal Cancer Reports"
DOI: 10.1007/s11888-018-0410-0
Abstract: Purpose of ReviewThe success of precision medicine relies heavily on biomarkers. Validated biomarkers that help stratify risk and guide treatments in patients with colorectal cancers are limited. With advances in genomics, immune landscapes and technological… read more here.
Keywords: medicine; evolving tissue; colorectal cancer; prognostic predictive ... See more keywords
Prognostic and predictive impact of consensus molecular subtypes and CRCAssigner classifications in metastatic colorectal cancer: a translational analysis of the TRIBE2 study
Sign Up to like & getrecommendations! Published in 2021 at "ESMO Open"
DOI: 10.1016/j.esmoop.2021.100073
Abstract: Introduction The consensus molecular subtypes (CMS) demonstrated prognostic value in metastatic colorectal cancer (mCRC). Similarly, a prognostic impact was suggested for the pre-consensus CRCAssigner (CRCA) classifier in early stages. The potential predictive role of these… read more here.
Keywords: pfs pfs2; impact; predictive impact; cms ... See more keywords
Prognostic and predictive capacity of tumor infiltrating lymphocytes in the MA.20 regional node radiotherapy trial
Sign Up to like & getrecommendations! Published in 2025 at "NPJ Breast Cancer"
DOI: 10.1038/s41523-025-00821-z
Abstract: Prognostic and predictive value of immune infiltrates in the context of regional nodal radiation (RNI) for breast cancer has not been assessed. Stromal tumor infiltrating lymphocytes (sTILs) were assessed on scanned images of hematoxylin and… read more here.
Keywords: cd8 stils; prognostic predictive; tumor infiltrating; dfs ... See more keywords
Pharmacodynamic, prognostic, and predictive biomarkers in severe and critical COVID-19 patients treated with sirukumab
Sign Up to like & getrecommendations! Published in 2024 at "Scientific Reports"
DOI: 10.1038/s41598-024-74196-9
Abstract: We examined candidate biomarkers for efficacy outcomes in hospitalized COVID-19 patients who were treated with sirukumab, an IL-6 neutralizing antibody, in a randomized, double-blind, placebo-controlled, phase 2 trial. Between May 2020 and March 2021, 209… read more here.
Keywords: critical covid; covid patients; prognostic predictive; covid ... See more keywords
Prognostic and predictive implications of tumor suppressor gene alterations in non-small cell lung cancer
Sign Up to like & getrecommendations! Published in 2025 at "Scientific Reports"
DOI: 10.1038/s41598-025-18662-y
Abstract: In addition to identifying alterations suitable for molecularly targeted therapy (TT), comprehensive genomic profiling (CGP) may convey prognostic/predictive information in advanced non-small-cell lung cancer (aNSCLC). We investigated the impact of tumor suppressor gene alterations (TSGAs)… read more here.
Keywords: lung cancer; non small; prognostic predictive; small cell ... See more keywords