Prognostic, predictive, and pharmacogenomic assessments of CDX2 refine stratification of colorectal cancer
Sign Up to like & getrecommendations! Published in 2018 at "Molecular Oncology"
DOI: 10.1002/1878-0261.12347
Abstract: We aimed to refine the value of CDX2 as an independent prognostic and predictive biomarker in colorectal cancer (CRC) according to disease stage and chemotherapy sensitivity in preclinical models. CDX2 expression was evaluated in 1045… read more here.
Keywords: chemotherapy; colorectal cancer; prognostic predictive; stage ... See more keywords
Reply to Neutrophil‐to‐lymphocyte ratio as a bladder cancer biomarker: Assessing prognostic and predictive value in SWOG 8710
Sign Up to like & getrecommendations! Published in 2017 at "Cancer"
DOI: 10.1002/cncr.30871
Abstract: In their letter, Dolan and McMillan raise several important points. First, many studies have concluded that the neutrophil-to-lymphocyte ratio (NLR) is a cancer biomarker. Second, the majority of studies analyzed NLR as a dichotomized variable.… read more here.
Keywords: cancer biomarker; ratio; neutrophil lymphocyte; prognostic predictive ... See more keywords
Evaluation of the circulating MicroRNA‐495 and Stat3 as prognostic and predictive biomarkers for lower extremity deep venous thrombosis
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.26633
Abstract: This study aims to elucidate the prognostic and predictive biomarker of miR‐495 and Stat3 in peripheral blood in relation to lower extremity deep venous thrombosis (DVT). Patients with lower limb fractures were assigned into case… read more here.
Keywords: lower extremity; mir 495; stat3; prognostic predictive ... See more keywords
A review of prognostic and predictive biomarkers in breast cancer
Sign Up to like & getrecommendations! Published in 2022 at "Clinical and Experimental Medicine"
DOI: 10.1007/s10238-021-00781-1
Abstract: Breast cancer (BC) is a common cancer all over the world that affects women. BC is one of the leading causes of cancer mortality in women, which today has decreased with the advancement of technology… read more here.
Keywords: cancer; predictive biomarkers; review prognostic; biomarkers breast ... See more keywords
Prognostic and predictive value of circulating tumor cells and CXCR4 expression as biomarkers for a CXCR4 peptide antagonist in combination with carboplatin-etoposide in small cell lung cancer: exploratory analysis of a phase II study
Sign Up to like & getrecommendations! Published in 2017 at "Investigational New Drugs"
DOI: 10.1007/s10637-017-0446-z
Abstract: SummaryBackground Circulating tumor cells (CTCs) and chemokine (C-X-C motif) receptor 4 (CXCR4) expression in CTCs and tumor tissue were evaluated as prognostic or predictive markers of CXCR4 peptide antagonist LY2510924 plus carboplatin-etoposide (CE) versus CE… read more here.
Keywords: cxcr4 expression; prognostic predictive; ctcs; tumor ... See more keywords
Prognostic and predictive impact of MGMT promoter methylation status in high risk grade II glioma
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Neuro-Oncology"
DOI: 10.1007/s11060-022-03955-3
Abstract: MGMT promoter methylation has been associated with favorable prognosis and survival outcomes in patients with glioblastoma and WHO grade III glioma. However, the effects of promoter methylation of MGMT in patients with WHO grade II… read more here.
Keywords: methylation; grade glioma; prognostic predictive; mgmt ... See more keywords
Evolving Tissue and Circulating Biomarkers as Prognostic and Predictive Tools in Colorectal Cancer
Sign Up to like & getrecommendations! Published in 2018 at "Current Colorectal Cancer Reports"
DOI: 10.1007/s11888-018-0410-0
Abstract: Purpose of ReviewThe success of precision medicine relies heavily on biomarkers. Validated biomarkers that help stratify risk and guide treatments in patients with colorectal cancers are limited. With advances in genomics, immune landscapes and technological… read more here.
Keywords: medicine; evolving tissue; colorectal cancer; prognostic predictive ... See more keywords
Prognostic and predictive impact of consensus molecular subtypes and CRCAssigner classifications in metastatic colorectal cancer: a translational analysis of the TRIBE2 study
Sign Up to like & getrecommendations! Published in 2021 at "ESMO Open"
DOI: 10.1016/j.esmoop.2021.100073
Abstract: Introduction The consensus molecular subtypes (CMS) demonstrated prognostic value in metastatic colorectal cancer (mCRC). Similarly, a prognostic impact was suggested for the pre-consensus CRCAssigner (CRCA) classifier in early stages. The potential predictive role of these… read more here.
Keywords: pfs pfs2; impact; predictive impact; cms ... See more keywords
Update on prognostic and predictive biomarkers of breast cancer.
Sign Up to like & getrecommendations! Published in 2022 at "Seminars in diagnostic pathology"
DOI: 10.1053/j.semdp.2022.06.015
Abstract: Breast cancer represents a heterogeneous group of human cancer at both histological and molecular levels. Estrogen receptor (ER), progesterone receptor (PR) and human epidermal growth factor receptor 2 (HER2) are the most commonly used biomarkers… read more here.
Keywords: predictive biomarkers; biomarkers breast; breast cancer; cancer ... See more keywords
Prognostic and predictive factors on overall survival and surgical outcomes in pancreatic neuroendocrine tumors: recent advances and controversies
Sign Up to like & getrecommendations! Published in 2019 at "Expert Review of Anticancer Therapy"
DOI: 10.1080/14737140.2019.1693893
Abstract: ABSTRACT Introduction: Recent advances in diagnostic modalities and therapeutic agents have raised the importance of prognostic factors in predicting overall survival, as well as predictive factors for surgical outcomes, in tailoring therapeutic strategies of patients… read more here.
Keywords: predictive factors; pancreatic neuroendocrine; surgical outcomes; prognostic predictive ... See more keywords
Distinguishing prognostic and predictive biomarkers: an information theoretic approach
Sign Up to like & getrecommendations! Published in 2018 at "Bioinformatics"
DOI: 10.1093/bioinformatics/bty515
Abstract: Fig. 2. When biomarkers have both prognostic/predictive strength (M-1) VT achieves higher TPR, otherwise (M-2) the gains in TPR are vanishing. In terms of FNRProg:, VT always has very high error rate on selecting solely… read more here.
Keywords: information theoretic; biomarkers information; theoretic approach; predictive biomarkers ... See more keywords