Identification of a novel prognostic signature correlated with epithelial‐mesenchymal transition, N6‐methyladenosine modification, and immune infiltration in colorectal cancer
Sign Up to like & getrecommendations! Published in 2022 at "Cancer Medicine"
DOI: 10.1002/cam4.5384
Abstract: Colorectal cancer (CRC) is a commonly diagnosed human malignancy worldwide. Both epithelial‐mesenchymal transition (EMT) and N6‐methyladenosine (m6A) modification play a crucial role in CRC development. This study aimed to construct a prognostic signature based on… read more here.
Keywords: modification; mesenchymal transition; prognostic signature; colorectal cancer ... See more keywords
Development and validation of a robust epithelial-mesenchymal transition (EMT)-related prognostic signature for hepatocellular carcinoma.
Sign Up to like & getrecommendations! Published in 2021 at "Clinics and research in hepatology and gastroenterology"
DOI: 10.1016/j.clinre.2020.101587
Abstract: OBJECTIVE Epithelial-to-mesenchymal transition (EMT) is an essential biological process of cancer progression associated with increased metastatic potential and initiation. Herein, we aimed to develop and validate a robust EMT-related prognostic signature that could predict the… read more here.
Keywords: emt related; prognostic signature; hcc; analysis ... See more keywords
Analysis of immune subtypes based on immunogenomic profiling identifies prognostic signature for cutaneous melanoma.
Sign Up to like & getrecommendations! Published in 2020 at "International immunopharmacology"
DOI: 10.1016/j.intimp.2020.107162
Abstract: Skin cutaneous melanoma (SKCM) is the most invasive form of skin cancer with poor prognosis. Growing evidence has demonstrated that tumor immune microenvironment plays a key contributing role in tumorigenesis and predicting clinical outcomes. The… read more here.
Keywords: immune; prognostic signature; cutaneous melanoma; signature ... See more keywords
Identification of survival-related genes and a novel gene-based prognostic signature involving the tumor microenvironment of uveal melanoma.
Sign Up to like & getrecommendations! Published in 2021 at "International immunopharmacology"
DOI: 10.1016/j.intimp.2021.107816
Abstract: Uveal melanoma (UM) is the most common primary intraocular malignant tumor in adults and almost fifty percent of patients subsequently develop systemic metastases usually involving the liver. The tumor microenvironment (TME) is crucial to the… read more here.
Keywords: prognostic signature; based prognostic; gene based; gene ... See more keywords
An immune landscape based prognostic signature predicts the immune status and immunotherapeutic responses of patients with colorectal cancer.
Sign Up to like & getrecommendations! Published in 2020 at "Life sciences"
DOI: 10.1016/j.lfs.2020.118368
Abstract: AIMS Colorectal cancer (CRC) is one of the most common cancers with poor prognosis worldwide. The advent of immunotherapy has greatly improved survival in refractory patients of CRC. In this study, we aimed to identify… read more here.
Keywords: prognostic signature; immunotherapeutic responses; crc; immune landscape ... See more keywords
Development of a novel transcription factors-related prognostic signature for serous ovarian cancer
Sign Up to like & getrecommendations! Published in 2021 at "Scientific Reports"
DOI: 10.1038/s41598-021-86294-z
Abstract: Growing evidence suggest that transcription factors (TFs) play vital roles in serous ovarian cancer (SOC). In the present study, TFs mRNA expression profiles of 564 SOC subjects in the TCGA database, and 70 SOC subjects… read more here.
Keywords: prognostic signature; risk; related prognostic; transcription factors ... See more keywords
Chromosome instability-associated prognostic signature and cluster investigation for cutaneous melanoma cases.
Sign Up to like & getrecommendations! Published in 2023 at "IET systems biology"
DOI: 10.1049/syb2.12064
Abstract: Chromosomal instability (CIN) is closely associated to the early detection of several clinical tumours. In this study, the authors first established a novel prognostic model of melanoma using the hub genes of CIN, based on… read more here.
Keywords: melanoma; instability; melanoma cases; prognostic signature ... See more keywords
Identification and Validation of Molecular Subtype and Prognostic Signature for Bladder Cancer Based on Neutrophil Extracellular Traps
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Investigation"
DOI: 10.1080/07357907.2023.2179063
Abstract: Abstract Neutrophil extracellular traps (NETs) could promote tumor growth and distant metastases. Molecular subtypes of bladder cancer were identified with consensus cluster analysis. A NETs-related prognostic signature was constructed with LASSO cox regression analysis. As… read more here.
Keywords: prognostic signature; bladder cancer; cancer; neutrophil extracellular ... See more keywords
Bioinformatics identification and validation of aging-related molecular subtype and prognostic signature in sarcoma.
Sign Up to like & getrecommendations! Published in 2023 at "Cancer investigation"
DOI: 10.1080/07357907.2023.2209638
Abstract: Aging could regulate many biological processes in malignancies by regulating cell senescence. Consensus cluster analysis was conducted to differentiate TCGA sarcoma cases. LASSO cox regression analysis was performed to construct an aging-related prognostic signature. We… read more here.
Keywords: sarcoma; prognostic signature; identification validation; aging related ... See more keywords
A novel DNA methylation 10-CpG prognostic signature of disease-free survival reveal that MYBL2 is associated with high risk in prostate cancer
Sign Up to like & getrecommendations! Published in 2020 at "Expert Review of Anticancer Therapy"
DOI: 10.1080/14737140.2020.1838280
Abstract: ABSTRACT Background Prostate cancer (PC) is the most common non-cutaneous malignancy among men in the western world. However, heterogeneity remains a pressing clinical problem. Research design and methods The least absolute shrinkage and selection operator… read more here.
Keywords: mybl2; prognostic signature; dna methylation; prostate cancer ... See more keywords
Constructing a new prognostic signature of gastric cancer based on multiple data sets.
Sign Up to like & getrecommendations! Published in 2021 at "Bioengineered"
DOI: 10.1080/21655979.2021.1940030
Abstract: In order to explore new prediction methods and key genes for gastric cancer. Firstly, we downloaded the 6 original sequencing data of gastric cancer on the Illumina HumanHT-12 platform from Array Expression and Gene Expression… read more here.
Keywords: prognostic signature; gastric cancer; constructing new; new prognostic ... See more keywords