Epigenetic alterations in glioblastomas: Diagnostic, prognostic and therapeutic relevance.
Sign Up to like & getrecommendations! Published in 2022 at "International journal of cancer"
DOI: 10.1002/ijc.34381
Abstract: Glioblastoma, the most common and heterogeneous tumor affecting brain parenchyma, is dismally characterized by a very poor prognosis. Thus, the search of new, more effective treatments is a vital need. Here, we will review the… read more here.
Keywords: epigenetic alterations; alterations glioblastomas; prognostic therapeutic; therapeutic relevance ... See more keywords
HSPA6, a novel prognostic and therapeutic biomarker, associated with Ming classification in gastric cancer
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Clinical Laboratory Analysis"
DOI: 10.1002/jcla.24763
Abstract: This study aimed to explore the clinical relevance of heat shock protein family A member 6 (HSPA6) in gastric cancer (GC) and its effect on GC cell proliferation. read more here.
Keywords: novel prognostic; prognostic therapeutic; gastric cancer; hspa6 novel ... See more keywords
Prognostic and therapeutic implications of NHERF1 expression and regulation in colorectal cancer
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Surgical Oncology"
DOI: 10.1002/jso.25805
Abstract: Na+/H+ exchanger regulatory factor 1 (NHERF1) has been implicated in the tumorigenesis of several cancer types and is a potential therapeutic target. The current study evaluated the relationship between NHERF1 expression and clinical outcome in… read more here.
Keywords: colorectal cancer; therapeutic implications; nherf1 expression; cancer ... See more keywords
Exploring the prognostic and therapeutic utility of expanded mutation profiling in appendix peritoneal metastasis managed with CRS/HIPEC
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Surgical Oncology"
DOI: 10.1002/jso.26439
Abstract: Interrogation of cancers with next‐generation sequencing (NGS) mutation panels has become widely utilized, identifying prognostic and actionable mutations. This study explored the value of expanded mutation analysis in appendix peritoneal metastases (APM). read more here.
Keywords: expanded mutation; appendix peritoneal; exploring prognostic; therapeutic utility ... See more keywords
Integrative Proteomic and Pharmacological Analysis of Colon Cancer Reveals the Classical Lipogenic Pathway with Prognostic and Therapeutic Opportunities.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of proteome research"
DOI: 10.1021/acs.jproteome.2c00646
Abstract: Despite recent advancements, the high mortality rate remains a concern in colon cancer (CAC). Identification of therapeutic markers could prove to be a great asset in CAC management. Multiple studies have reported hyperactivation of de… read more here.
Keywords: prognostic therapeutic; colon cancer; pathway; cac ... See more keywords
The prognostic and therapeutic potentials of CTLA-4 in hematological malignancies
Sign Up to like & getrecommendations! Published in 2022 at "Expert Opinion on Therapeutic Targets"
DOI: 10.1080/14728222.2022.2170781
Abstract: ABSTRACT Introduction Hematological Malignancies (HMs) are a group of progressive, difficult-to-treat, and highly recurrent diseases. A suppressed phenotype of the immune system is present in HMs and growing evidence indicates the role of Cytotoxic T… read more here.
Keywords: potentials ctla; hms; therapeutic potentials; prognostic therapeutic ... See more keywords
Diagnostic, prognostic and therapeutic role of CD30 in lymphoma
Sign Up to like & getrecommendations! Published in 2017 at "Expert Review of Hematology"
DOI: 10.1080/17474086.2017.1270202
Abstract: ABSTRACT Introduction: CD30 is a cell surface receptor expressed in classical Hodgkin lymphoma (HL), anaplastic large cell lymphoma (ALCL), and many other lymphomas to a variable degree. It has been identified as an important therapeutic… read more here.
Keywords: lymphoma; role cd30; cd30; diagnostic prognostic ... See more keywords
Diagnostic, Prognostic, and Therapeutic Potencies of Circulating miRNAs in Acute Myocardial Infarction.
Sign Up to like & getrecommendations! Published in 2019 at "Critical reviews in eukaryotic gene expression"
DOI: 10.1615/critreveukaryotgeneexpr.2019028211
Abstract: Acute myocardial infarction (AMI), or heart attack, is a major public health problem, responsible for 3 to 4 million deaths each year. Despite great improvements in diagnostic and therapeutic strategies, it remains one of the… read more here.
Keywords: therapeutic potencies; acute myocardial; diagnostic prognostic; prognostic therapeutic ... See more keywords
Molecular subtypes of gastrointestinal stromal tumors and their prognostic and therapeutic implications.
Sign Up to like & getrecommendations! Published in 2017 at "Future oncology"
DOI: 10.2217/fon-2016-0192
Abstract: Gastrointestinal stromal tumors (GISTs) are composed of various molecular subtypes, with differing prognostic and predictive relevance. Previously, tumors lacking mutations in the KIT and PDGFRA genes have been designated as 'wild-type' GISTs; however, they represent… read more here.
Keywords: subtypes gastrointestinal; tumors prognostic; gastrointestinal stromal; stromal tumors ... See more keywords
Gut microbiota and cancer immunotherapy: prognostic and therapeutic implications.
Sign Up to like & getrecommendations! Published in 2020 at "Future oncology"
DOI: 10.2217/fon-2019-0783
Abstract: The immune checkpoint inhibitors have opened new horizons in oncology. Although the indications for the use of Immune checkpoint inhibitors in cancer patients are expanding, there is still a need for markers that can aid… read more here.
Keywords: microbiota; immunotherapy; cancer immunotherapy; cancer ... See more keywords
Evaluating the Prognostic and Therapeutic Potentials of the Proteasome 26S Subunit, ATPase (PSMC) Family of Genes in Lung Adenocarcinoma: A Database Mining Approach
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2022.935286
Abstract: This study explored the prognostic and therapeutic potentials of multiple Proteasome 26S Subunit, ATPase (PSMC) family of genes (PSMC1-5) in lung adenocarcinoma (LUAD) diagnosis and treatment. All the PSMCs were found to be differentially expressed… read more here.
Keywords: atpase psmc; therapeutic potentials; prognostic therapeutic; subunit atpase ... See more keywords