Programmable protein circuit design
Sign Up to like & getrecommendations! Published in 2021 at "Cell"
DOI: 10.1016/j.cell.2021.03.007
Abstract: A fundamental challenge in synthetic biology is to create molecular circuits that can program complex cellular functions. Because proteins can bind, cleave, and chemically modify one another and interface directly and rapidly with endogenous pathways,… read more here.
Keywords: programmable protein; circuit; protein circuit; biology ... See more keywords
Rapid and Programmable Protein Mutagenesis Using Plasmid Recombineering.
Sign Up to like & getrecommendations! Published in 2017 at "ACS synthetic biology"
DOI: 10.1021/acssynbio.7b00112
Abstract: Comprehensive and programmable protein mutagenesis is critical for understanding structure-function relationships and improving protein function. There is thus a need for robust and unbiased molecular biological approaches for the construction of the requisite comprehensive protein… read more here.
Keywords: protein; mutagenesis; rapid programmable; plasmid recombineering ... See more keywords
Programmable protein circuits in living cells
Sign Up to like & getrecommendations! Published in 2018 at "Science"
DOI: 10.1126/science.aat5062
Abstract: Building smarter synthetic biological circuits Synthetic genetic and biological regulatory circuits can enable logic functions to form the basis of biological computing; synthetic biology can also be used to control cell behaviors (see the Perspective… read more here.
Keywords: protein; circuits living; circuit; living cells ... See more keywords
Self-assembling functional programmable protein array for studying protein–protein interactions in malaria parasites
Sign Up to like & getrecommendations! Published in 2018 at "Malaria Journal"
DOI: 10.1186/s12936-018-2414-2
Abstract: BackgroundPlasmodium vivax is the most widespread malarial species, causing significant morbidity worldwide. Knowledge is limited regarding the molecular mechanism of invasion due to the lack of a continuous in vitro culture system for these species.… read more here.
Keywords: protein; studying protein; protein protein; protein array ... See more keywords