Programming Aptamer-Protein Complexation Kinetics via Modulation of G-Quadruplex Secondary Structure.
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DOI: 10.1021/jacs.5c10067
Abstract: Aptamers have emerged as key receptors in the pursuit of universal biomolecular monitoring. However, while many aptamers possess excellent association rates, they tend to exhibit slow dissociation kinetics. While these slow off-rates are great for… read more here.
Keywords: programming aptamer; structure; kinetics via; protein complexation ... See more keywords