Programming DNA Aptamer Arrays of Prescribed Spatial Features with Enhanced Bioavailability and Cell Growth Modulation.
Sign Up to like & getrecommendations! Published in 2022 at "Nano letters"
DOI: 10.1021/acs.nanolett.2c03377
Abstract: Epithelial cell adhesion molecules (EpCAMs) play pivotal roles in tumorigenesis in many cancer types, which is reported to reside within nano- to microscale membrane domains, forming small clusters. We propose that building multivalent ligands that… read more here.
Keywords: cell; bioavailability; arrays prescribed; aptamer arrays ... See more keywords
Programming DNA Self-Assembly by Geometry†.
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DOI: 10.1021/jacs.2c02456
Abstract: This manuscript introduces geometry as a means to program the tile-based DNA self-assembly in two and three dimensions. This strategy complements the sequence-focused programmable assembly. DNA crystal assembly critically relies on intermotif, sticky-end cohesion, which… read more here.
Keywords: dna self; self assembly; programming dna; geometry ... See more keywords
Programming DNA Circuits for Controlled Immunostimulation through CpG Oligodeoxynucleotide Delivery.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.2c09359
Abstract: Herein, we present a DNA circuit programmed for the delivery of CpG oligodeoxynucleotides (CpG ODNs) with the pharmacological immunostimulation function. The circuit employs a complementary DNA (cDNA) strand to deactivate the biological function of CpG… read more here.
Keywords: dna; circuit; immunostimulation; delivery ... See more keywords