A multifaceted role of progranulin in regulating amyloid-beta dynamics and responses
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DOI: 10.26508/lsa.202000874
Abstract: Progranulin deficiency leads to decreased levels of human APP and Aβ in a sex- and age-dependent manner and enhanced inflammatory and lysosomal responses in the plaque-associated microglia. Haploinsufficiency of progranulin (PGRN) is a leading cause… read more here.
Keywords: progranulin regulating; role progranulin; progranulin; pgrn ... See more keywords