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   Articles with "progression" as a keyword



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Potential Role and Limitations of Estimated Glomerular Filtration Rate Slope Assessment in Cardiovascular Trials: A Review.

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recommendations! Published in 2022 at "JAMA cardiology"

DOI: 10.1001/jamacardio.2021.5151

Abstract: Importance Cardiovascular trials have traditionally been underpowered to assess advanced chronic kidney disease (CKD) outcomes, and when included as a secondary end point, trials have used progression of CKD as incidence of some variation of… read more here.

Keywords: glomerular filtration; slope; estimated glomerular; progression ... See more keywords
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Progression and Regression of Chronic Kidney Disease by Age Among Adults in a Population-Based Cohort in Alberta, Canada

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recommendations! Published in 2021 at "JAMA Network Open"

DOI: 10.1001/jamanetworkopen.2021.12828

Abstract: Key Points Question How likely is regression of mild to severe chronic kidney disease (CKD) in adults? Findings In this population-based cohort study of adults with incident CKD, the 5-year probability of regression was similar… read more here.

Keywords: regression; chronic kidney; ckd; progression ... See more keywords
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Identification and Validation of Plasma Metabolomic Signatures in Precancerous Gastric Lesions That Progress to Cancer.

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recommendations! Published in 2021 at "JAMA network open"

DOI: 10.1001/jamanetworkopen.2021.14186

Abstract: Importance Metabolic deregulation plays an important role in gastric cancer (GC) development. To date, no studies have comprehensively explored the metabolomic profiles along the cascade of gastric lesions toward GC. Objective To draw a metabolic… read more here.

Keywords: gastric lesions; risk; validation; metabolomic signatures ... See more keywords
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Serum Neurofilament Light and Multiple Sclerosis Progression Independent of Acute Inflammation

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recommendations! Published in 2022 at "JAMA Network Open"

DOI: 10.1001/jamanetworkopen.2021.47588

Abstract: This cohort study investigates serum neurofilament light concentration as a biomarker associated with disability progression in multiple sclerosis in the absence of acute inflammation. read more here.

Keywords: neurofilament light; progression; acute inflammation; multiple sclerosis ... See more keywords
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Association of Upfront Peptide Receptor Radionuclide Therapy With Progression-Free Survival Among Patients With Enteropancreatic Neuroendocrine Tumors

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recommendations! Published in 2022 at "JAMA Network Open"

DOI: 10.1001/jamanetworkopen.2022.0290

Abstract: This cohort study assesses the association of upfront peptide receptor radionuclide therapy (PRRT) vs upfront chemotherapy or targeted therapy with progression-free survival among patients in Italy with enteropancreatic neuroendocrine tumors who experienced disease progression after… read more here.

Keywords: receptor radionuclide; association upfront; progression; peptide receptor ... See more keywords
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Association of Cerebrospinal Fluid Neurofilament Heavy Protein Levels With Clinical Progression in Patients With Parkinson Disease

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recommendations! Published in 2022 at "JAMA Network Open"

DOI: 10.1001/jamanetworkopen.2022.23821

Abstract: Key Points Question Are cerebrospinal fluid (CSF) neurofilament heavy (cNfH) levels associated with clinical progression in patients with Parkinson disease? Findings In this cohort study of 404 patients with Parkinson disease, higher baseline cNfH levels… read more here.

Keywords: patients parkinson; progression; parkinson disease; cerebrospinal fluid ... See more keywords
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Progression of Vascular Calcification and Clinical Outcomes in Patients Receiving Maintenance Dialysis

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recommendations! Published in 2023 at "JAMA Network Open"

DOI: 10.1001/jamanetworkopen.2023.10909

Abstract: Key Points Question What are the speed and prevalence of vascular calcification (VC) progression, and how is VC progression associated with the risk of cardiovascular (CV) events and death among patients in China receiving maintenance… read more here.

Keywords: receiving maintenance; progression; maintenance dialysis; calcification ... See more keywords
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Measurement of Dimensions of Self-awareness of Memory Function and Their Association With Clinical Progression in Cognitively Normal Older Adults

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recommendations! Published in 2023 at "JAMA Network Open"

DOI: 10.1001/jamanetworkopen.2023.9964

Abstract: Key Points Question Are separate, item-based measures of unawareness or heightened awareness of memory function associated with future progression from preclinical to symptomatic Alzheimer disease? Findings In this cohort study of 436 older adults, worse… read more here.

Keywords: older adults; awareness memory; progression; memory function ... See more keywords
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Association of Inflammation and Disability Accrual in Patients With Progressive-Onset Multiple Sclerosis

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recommendations! Published in 2018 at "JAMA Neurology"

DOI: 10.1001/jamaneurol.2018.2109

Abstract: Importance The role of inflammatory disease activity as a determinant of disability in progressive-onset multiple sclerosis (MS) remains contested. Objective To examine the association of superimposed relapses in progressive-onset MS on disease outcomes. Design, Setting,… read more here.

Keywords: disability; progressive onset; disease; relapse ... See more keywords
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Association Between Circulating Tumor DNA and Pseudoprogression in Patients With Metastatic Melanoma Treated With Anti–Programmed Cell Death 1 Antibodies

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recommendations! Published in 2018 at "JAMA Oncology"

DOI: 10.1001/jamaoncol.2017.5332

Abstract: Importance Longitudinal circulating tumor DNA (ctDNA) has been shown to predict response and survival in patients with metastatic melanoma treated with anti–programmed cell death 1 (PD-1) antibodies. Pseudoprogression, defined as radiologic finding of disease progression… read more here.

Keywords: ctdna; response; ctdna profile; disease ... See more keywords
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Radiographic Progression-Free Survival as a Clinically Meaningful End Point in Metastatic Castration-Resistant Prostate Cancer: The PREVAIL Randomized Clinical Trial

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recommendations! Published in 2018 at "JAMA Oncology"

DOI: 10.1001/jamaoncol.2017.5808

Abstract: Importance Drug development for metastatic castration-resistant prostate cancer has been limited by a lack of clinically relevant trial end points short of overall survival (OS). Radiographic progression-free survival (rPFS) as defined by the Prostate Cancer… read more here.

Keywords: progression; rpfs; metastatic castration; prostate cancer ... See more keywords