Articles with "progression activating" as a keyword



Phospholipase D1 promotes cervical cancer progression by activating the RAS pathway

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Published in 2022 at "Journal of Cellular and Molecular Medicine"

DOI: 10.1111/jcmm.17439

Abstract: This study aimed to further investigate the effect of PLD1 on the biological characteristics of human cervical cancer (CC) cell line, CASKI and the potential related molecular mechanism. CRISPR/Cas9 genome editing technology was used to… read more here.

Keywords: caski cells; cervical cancer; activating ras; ras pathway ... See more keywords
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DJ-1 promotes osteosarcoma progression through activating CDK4/RB/E2F1 signaling pathway

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Published in 2022 at "Frontiers in Oncology"

DOI: 10.3389/fonc.2022.1036401

Abstract: Osteosarcoma (OS) is a primary malignant tumor of the bone characterized by poor prognosis due to chemotherapy resistance and high recurrence rates. DJ-1 (PARK7) is known as an oncogene and its abnormal expression is related… read more here.

Keywords: progression; promotes osteosarcoma; cdk4 e2f1; activating cdk4 ... See more keywords