RFX5 promotes the progression of hepatocellular carcinoma through transcriptional activation of KDM4A
Sign Up to like & getrecommendations! Published in 2020 at "Scientific Reports"
DOI: 10.1038/s41598-020-71403-1
Abstract: Regulatory factor X-5 (RFX5) represents a key transcription regulator of MHCII gene expression in the immune system. This study aims to explore the molecular mechanisms and biological significance of RFX5. Firstly, by analyzing ENCODE chromatin… read more here.
Keywords: rfx5 promotes; kdm4a; progression hepatocellular; rfx5 ... See more keywords
microRNA-378a-3p regulates the progression of hepatocellular carcinoma by regulating PD-L1 and STAT3
Sign Up to like & getrecommendations! Published in 2022 at "Bioengineered"
DOI: 10.1080/21655979.2022.2031408
Abstract: ABSTRACT Programmed death ligand 1 (PD-L1) plays an essential role in the development or progression of hepatocellular carcinoma (HCC). MicroRNAs (miRNAs) are small RNA molecules that regulate gene expression during normal and pathophysiological events. Here,… read more here.
Keywords: regulating stat3; mir 378a; hepatocellular carcinoma; progression hepatocellular ... See more keywords
HOXD3 was negatively regulated by YY1 recruiting HDAC1 to suppress progression of hepatocellular carcinoma cells via ITGA2 pathway
Sign Up to like & getrecommendations! Published in 2020 at "Cell Proliferation"
DOI: 10.1111/cpr.12835
Abstract: HOXD3 is associated with progression of multiple types of cancer. This study aimed to identify the association of YY1 with HOXD3‐ITGA2 axis in the progression of hepatocellular carcinoma. read more here.
Keywords: hepatocellular carcinoma; progression; progression hepatocellular; hoxd3 negatively ... See more keywords
UCK2 regulated by miR-139-3p regulates the progression of hepatocellular carcinoma cells.
Sign Up to like & getrecommendations! Published in 2022 at "Future oncology"
DOI: 10.2217/fon-2021-0271
Abstract: Objective: This study mainly explores how UCK2 impacts the progression of hepatocellular carcinoma (HCC). Methods: Mature miRNA and mRNA expression data along with the clinical data of HCC were provided by The Cancer Genome Atlas… read more here.
Keywords: hepatocellular carcinoma; cell; progression hepatocellular; hcc ... See more keywords
LncRNA FOXD2-AS1 facilitates the progression of hepatocellular carcinoma by regulating TWIST1.
Sign Up to like & getrecommendations! Published in 2023 at "European review for medical and pharmacological sciences"
DOI: 10.26355/eurrev_202305_32460
Abstract: OBJECTIVE The study aimed at elucidating the role of FOXD2-AS1 in facilitating the malignant progression of hepatocellular carcinoma (HCC) by regulating TWIST1. PATIENTS AND METHODS Relative levels of FOXD2-AS1 and TWIST1 in HCC tissues classified… read more here.
Keywords: foxd2 as1; hepatocellular carcinoma; hcc; progression hepatocellular ... See more keywords
Mer Tyrosine Kinase (MERTK) modulates liver fibrosis progression and hepatocellular carcinoma development
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.926236
Abstract: Background MerTK is a tyrosine kinase receptor that belongs to the TAM (Tyro3/Axl/Mer) receptor family. It is involved in different processes including cellular proliferation/survival, cellular adhesion/migration, and release of the inflammatory/anti-inflammatory cytokines. Although it is… read more here.
Keywords: hepatocellular carcinoma; mertk; progression hepatocellular; progression ... See more keywords
Translational Control of Metabolism and Cell Cycle Progression in Hepatocellular Carcinoma
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24054885
Abstract: The liver is a metabolic hub characterized by high levels of protein synthesis. Eukaryotic initiation factors, eIFs, control the first phase of translation, initiation. Initiation factors are essential for tumor progression and, since they regulate… read more here.
Keywords: hepatocellular carcinoma; eif4e eif6; progression hepatocellular; progression ... See more keywords