MBD2 Ablation Impairs Lymphopoiesis and Impedes Progression and Maintenance of T-ALL.
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DOI: 10.1158/0008-5472.can-17-1434
Abstract: Aberrant DNA methylation patterns in leukemia might be exploited for therapeutic targeting. In this study, we employed a genetically deficient mouse model to explore the role of the methylated DNA binding protein MBD2 in normal… read more here.
Keywords: wnt signaling; mbd2 ablation; mbd2; progression maintenance ... See more keywords