The role of microRNAs regulating the expression of matrix metalloproteinases (MMPs) in breast cancer development, progression, and metastasis
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.27445
Abstract: MicroRNAs (miRNAs) regulate several biological and physiological processes in mammalian cells, including cellular proliferation, differentiation, apoptosis, and metabolism. Recent studies have confirmed the alteration of them during the cancer development. Matrix metalloproteinases (MMPs), belonging to… read more here.
Keywords: cancer; progression metastasis; expression; cancer development ... See more keywords
Dissecting miRNA signature in colorectal cancer progression and metastasis.
Sign Up to like & getrecommendations! Published in 2020 at "Cancer letters"
DOI: 10.1016/j.canlet.2020.12.025
Abstract: Colorectal cancer (CRC) is the third most common cancer and leading cause of cancer related deaths worldwide. Despite recent advancements in surgical and molecular targeted therapies that improved the therapeutic efficacy in CRC, the 5… read more here.
Keywords: cancer; progression metastasis; colorectal cancer; crc ... See more keywords
Specificity protein 1: Its role in colorectal cancer progression and metastasis.
Sign Up to like & getrecommendations! Published in 2017 at "Critical reviews in oncology/hematology"
DOI: 10.1016/j.critrevonc.2017.02.024
Abstract: Specificity protein 1 (Sp1) is a widely expressed transcription factor that plays an important role in the promotion of oncogenes required for tumor survival, progression and metastasis. Sp1 is highly expressed in several cancers including… read more here.
Keywords: specificity protein; progression; progression metastasis; colorectal cancer ... See more keywords
TAMeless traitors: macrophages in cancer progression and metastasis
Sign Up to like & getrecommendations! Published in 2017 at "British Journal of Cancer"
DOI: 10.1038/bjc.2017.356
Abstract: Macrophages are conventionally classified into M1 and M2 subtypes according to their differentiation status and functional role in the immune system. However, accumulating evidence suggests that this binary classification system is insufficient to account for… read more here.
Keywords: cancer; progression metastasis; traitors macrophages; tameless traitors ... See more keywords
GATA3 Targets Semaphorin 3B in Mammary Epithelial Cells to Suppress Breast Cancer Progression and Metastasis
Sign Up to like & getrecommendations! Published in 2017 at "Oncogene"
DOI: 10.1038/onc.2017.165
Abstract: Semaphorin 3B (SEMA3B) is a secreted axonal guidance molecule that is expressed during development and throughout adulthood. Recently, SEMA3B has emerged as a tumor suppressor in non-neuronal cells. Here, we show that SEMA3B is a… read more here.
Keywords: cancer; progression metastasis; cancer progression; breast cancer ... See more keywords
Circular RNA circTNIK promotes tumor progression and metastasis in gastric cancer by regulating ZEB2.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of gastroenterology and hepatology"
DOI: 10.1111/jgh.16189
Abstract: BACKGROUND AND AIM Tumor progression and distant metastasis are the main causes of deaths in gastric cancer. Growing evidence revealed that circular RNAs (circRNAs) play critical role in the pathology of malignant disease, the role… read more here.
Keywords: progression metastasis; cancer; circtnik; gastric cancer ... See more keywords
Role of oral microbiome in oral oncogenesis, tumor progression and metastasis.
Sign Up to like & getrecommendations! Published in 2022 at "Molecular oral microbiology"
DOI: 10.1111/omi.12403
Abstract: Squamous cell carcinoma is the most common malignant tumor of the oral cavity and its adjacent sites, which endangers the physical and mental health of patients and has a complex etiology. Chronic infection is considered… read more here.
Keywords: progression metastasis; oral oncogenesis; oral microbiome; tumor ... See more keywords
Understanding the role of Cysteinyl leukotriene receptor signaling in cancer progression and metastasis
Sign Up to like & getrecommendations! Published in 2023 at "Physiology"
DOI: 10.1152/physiol.2023.38.s1.5733242
Abstract: Background: Cysteinyl leukotrienes (cys-LTs) are pro-inflammatory mediators which enhance inflammation through cysteinyl leukotriene receptor 1 (CysLT1R) and cysteinyl leukotriene receptor 2 (CysLT2R). Although cys-LTs and their receptors are mainly implicated in asthma and inflammation, recent… read more here.
Keywords: metastasis; progression metastasis; physiology; cysteinyl ... See more keywords
Abstract 2536: Intracellular Ctla4 overexpression promotes melanoma progression and metastasis
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Research"
DOI: 10.1158/1538-7445.am2023-2536
Abstract: Cytotoxic T Lymphocyte Antigen 4 (CTLA4) expressed on the surface of T cells is an important immunotherapeutic target in many cancers, including melanoma. However, we previously found highly upregulated expression of CTLA4 in BRAF/NRAS-mutant human… read more here.
Keywords: progression metastasis; melanoma progression; ctla4; melanoma ... See more keywords
Abstract LB156: Identified the ISG15 mediated extracellular vesicles drives ovarian cancer progression and metastasis: extracellular vesicular ISG15 is a potential biomarker and therapeutic target
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Research"
DOI: 10.1158/1538-7445.am2023-lb156
Abstract: Background & Objective: High-grade serous ovarian cancer (HGSOC) accounts for over 80% of all epithelial ovarian cancer (OC) diagnoses, and the majority of patients with HGSOC are diagnosed with advanced metastatic disease. Aberrant expression of… read more here.
Keywords: progression metastasis; cancer; ovarian cancer; isg15 ... See more keywords
Macrophages promote the progression of premalignant mammary lesions to invasive cancer.
Sign Up to like & getrecommendations! Published in 2017 at "Oncotarget"
DOI: 10.18632/oncotarget.14913
Abstract: Breast cancer initiation, progression and metastasis rely on a complex interplay between tumor cells and their surrounding microenvironment. Infiltrating immune cells, including macrophages, promote mammary tumor progression and metastasis; however, less is known about the… read more here.
Keywords: progression metastasis; macrophages promote; early stage; cancer ... See more keywords