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Published in 2019 at "Cell Reports"
DOI: 10.1016/j.celrep.2019.01.033
Abstract: Summary There is a need to identify biomarkers predictive of severe dengue. Single-cohort transcriptomics has not yielded generalizable results or parsimonious, predictive gene sets. We analyzed blood samples of dengue patients from seven gene expression…
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Keywords:
gene set;
progression severe;
dengue;
gene ... See more keywords
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Published in 2020 at "International Journal of Infectious Diseases"
DOI: 10.1016/j.ijid.2020.11.056
Abstract: Without an effective vaccine or specific treatment for dengue, the ability to accurately predict early progression to severe disease relies on patient triage and clinical management. Previous systematic reviews and meta-analyses have found significant heterogeneity…
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Keywords:
severe disease;
dengue;
progression severe;
meta ... See more keywords
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Published in 2021 at "Frontiers in Cardiovascular Medicine"
DOI: 10.3389/fcvm.2021.702507
Abstract: Background: Cardiovascular comorbidities such as hypertension and inflammatory response dysregulation are associated with worse COVID-19 prognoses. Different cytokines have been proposed to play vital pathophysiological roles in COVID-19 progression, but appropriate prognostic biomarkers remain lacking.…
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Keywords:
risk;
p70;
covid;
progression severe ... See more keywords
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Published in 2023 at "Tropical Medicine and Infectious Disease"
DOI: 10.3390/tropicalmed8020068
Abstract: This study aimed to assess the predictive performance of the National Early Warning Score 2 (NEWS2) to identify the early progression to severe disease in patients with community-acquired pneumonia (CAP). A prospective-cohort study was conducted…
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Keywords:
early progression;
progression;
cap;
progression severe ... See more keywords