Prohibitin promotes de-differentiation and is a potential therapeutic target in neuroblastoma.
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DOI: 10.1172/jci.insight.127130
Abstract: Gain of the long arm of chromosome 17 (17q) is a cytogenetic hallmark of high-risk neuroblastoma, yet its contribution to neuroblastoma pathogenesis remains incompletely understood. Combining whole-genome and RNA sequencing of neuroblastomas, we identified the… read more here.
Keywords: promotes differentiation; neuroblastoma; prohibitin promotes; differentiation potential ... See more keywords