miR‐4734 conditionally suppresses ER stress‐associated proinflammatory responses
Sign Up to like & getrecommendations! Published in 2022 at "FEBS Letters"
DOI: 10.1002/1873-3468.14548
Abstract: Prolonged metabolic stress can lead to severe pathologies. In metabolically challenged primary fibroblasts, we assigned a novel role for the poorly characterized miR‐4734 in restricting ATF4 and IRE1‐mediated upregulation of a set of proinflammatory cytokines… read more here.
Keywords: stress; conditionally suppresses; stress associated; 4734 conditionally ... See more keywords
The potency of common proinflammatory cytokines measurement for revealing the risk and severity of anxiety and depression in psoriasis patients
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Clinical Laboratory Analysis"
DOI: 10.1002/jcla.24643
Abstract: Proinflammatory cytokines mediate anxiety and depression in various ways, such as immunity, inflammation, and the hypothalamic–pituitary–adrenal axis. This study intended to further explore the linkage of common proinflammatory cytokine levels with anxiety and depression in… read more here.
Keywords: proinflammatory cytokines; common proinflammatory; proinflammatory; anxiety depression ... See more keywords
Recent Organic Photosensitizer Designs for Evoking Proinflammatory Regulated Cell Death in Antitumor Immunotherapy
Sign Up to like & getrecommendations! Published in 2023 at "Small Methods"
DOI: 10.1002/smtd.202201614
Abstract: In the past decades, immunotherapy has achieved a series of clinical successes in the field of cancer. However, existing therapeutic options usually show a low immune response to solid tumors caused by immunosuppressive “cold” tumor… read more here.
Keywords: cell death; immunotherapy; proinflammatory rcd; regulated cell ... See more keywords
An intervertebral disc whole organ culture system to investigate proinflammatory and degenerative disc disease condition
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Tissue Engineering and Regenerative Medicine"
DOI: 10.1002/term.2636
Abstract: The aim of this study was to compare the effect of different disease initiators of degenerative disc disease (DDD) within an intervertebral disc (IVD) organ culture system and to understand the interplay between inflammation and… read more here.
Keywords: proinflammatory; degenerative disc; condition; disease ... See more keywords
Rutin alleviates bisphenol A‐glycidyl methacrylate‐induced generation of proinflammatory mediators through the MAPK and NF‐κB pathways in macrophages
Sign Up to like & getrecommendations! Published in 2022 at "Environmental Toxicology"
DOI: 10.1002/tox.23711
Abstract: Bisphenol A‐glycidyl methacrylate (BisGMA) is a methacrylate monomer that is mainly used in three‐dimensional structures to reconstruct dental and bony defects. BisGMA has toxic and proinflammatory effects on macrophages. Rutin is a natural flavonol glycoside… read more here.
Keywords: methacrylate; generation; phosphorylation; rutin ... See more keywords
Graphene quantum dots suppress proinflammatory T cell responses via autophagy-dependent induction of tolerogenic dendritic cells.
Sign Up to like & getrecommendations! Published in 2017 at "Biomaterials"
DOI: 10.1016/j.biomaterials.2017.08.040
Abstract: Graphene quantum dots (GQD) are atom-thick nanodimensional carbon sheets with excellent physico-chemical and biological properties, making them attractive for application in theranostics. However, their immunoregulatory properties are insufficiently investigated, especially in human primary immune cells.… read more here.
Keywords: proinflammatory; graphene quantum; dots suppress; dendritic cells ... See more keywords
Melatonin mitigates thioacetamide‐induced hepatic fibrosis via antioxidant activity and modulation of proinflammatory cytokines and fibrogenic genes
Sign Up to like & getrecommendations! Published in 2018 at "Life Sciences"
DOI: 10.1016/j.lfs.2017.11.036
Abstract: Aims: The potential antifibrotic effects of melatonin against induced hepatic fibrosis were explored. Main methods: Rats were allocated into four groups: placebo; thioacetamide (TAA) (200 mg/kg bwt, i.p twice weekly for two months); melatonin (5… read more here.
Keywords: proinflammatory; proinflammatory cytokines; fibrogenic genes; hepatic fibrosis ... See more keywords
N-acetyl cysteine reverts the proinflammatory state induced by cigarette smoke extract in lung Calu-3 cells
Sign Up to like & getrecommendations! Published in 2018 at "Redox Biology"
DOI: 10.1016/j.redox.2018.03.006
Abstract: Chronic obstructive pulmonary disease (COPD) and cystic fibrosis (CF) are lethal pulmonary diseases. Cigarette consumption is the main cause for development of COPD, while CF is produced by mutations in the CFTR gene. Although these… read more here.
Keywords: proinflammatory state; proinflammatory; calu; treatment ... See more keywords
Maternal BCG scar is associated with increased infant proinflammatory immune responses
Sign Up to like & getrecommendations! Published in 2017 at "Vaccine"
DOI: 10.1016/j.vaccine.2016.11.079
Abstract: Introduction Prenatal exposures such as infections and immunisation may influence infant responses. We had an opportunity to undertake an analysis of innate responses in infants within the context of a study investigating the effects of… read more here.
Keywords: bcg scar; proinflammatory; maternal bcg; infant responses ... See more keywords
Fluoxetine and Curcumin Prevent the Alterations in Locomotor and Exploratory Activities and Social Interaction Elicited by Immunoinflammatory Activation in Zebrafish: Involvement of BDNF and Proinflammatory Cytokines.
Sign Up to like & getrecommendations! Published in 2023 at "ACS chemical neuroscience"
DOI: 10.1021/acschemneuro.2c00475
Abstract: The increase in proinflammatory cytokine expression causes behavioral changes consistent with sickness behavior, and this led to the suggestion that depression might be a psychoneuroimmunological phenomenon. Here, we evaluated the effects of the pretreatment with… read more here.
Keywords: expression; fluoxetine curcumin; bdnf; sickness behavior ... See more keywords
Activation of NF-κB and induction of proinflammatory cytokine expressions mediated by ORF7a protein of SARS-CoV-2
Sign Up to like & getrecommendations! Published in 2021 at "Scientific Reports"
DOI: 10.1038/s41598-021-92941-2
Abstract: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent for coronavirus disease 2019 (COVID-19) that emerged in human populations recently. Severely ill COVID-19 patients exhibit the elevation of proinflammatory cytokines, and such an… read more here.
Keywords: proinflammatory; covid patients; orf7a protein; cytokine expressions ... See more keywords