IL‐1α inhibits proliferation and adipogenic differentiation of human adipose‐derived mesenchymal stem cells through NF‐κB‐ and ERK1/2‐mediated proinflammatory cytokines
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DOI: 10.1002/cbin.10932
Abstract: Dysfunctional adipogenesis such as subcutaneous lipoatrophy is closely related to insulin resistance and metabolic disorders. Although the expression or release of the cytokine interleukin‐1α (IL‐1α) is known to increase in adipose tissue in response to… read more here.
Keywords: proinflammatory cytokines; proliferation adipogenic; differentiation human; adipogenic differentiation ... See more keywords
Yes‐Associated Protein in Kupffer Cells Enhances the Production of Proinflammatory Cytokines and Promotes the Development of Nonalcoholic Steatohepatitis
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DOI: 10.1002/hep.30990
Abstract: Yes‐associated protein (YAP) plays an important role in hepatocarcinogenesis, although the potential role of YAP in non‐neoplastic liver diseases remains largely unknown. We report herein that YAP in Kupffer cells (KCs) enhances the production of… read more here.
Keywords: associated protein; proinflammatory cytokines; kupffer cells; production proinflammatory ... See more keywords
The potency of common proinflammatory cytokines measurement for revealing the risk and severity of anxiety and depression in psoriasis patients
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Clinical Laboratory Analysis"
DOI: 10.1002/jcla.24643
Abstract: Proinflammatory cytokines mediate anxiety and depression in various ways, such as immunity, inflammation, and the hypothalamic–pituitary–adrenal axis. This study intended to further explore the linkage of common proinflammatory cytokine levels with anxiety and depression in… read more here.
Keywords: proinflammatory cytokines; common proinflammatory; proinflammatory; anxiety depression ... See more keywords
Individual genetic variability mainly of Proinflammatory cytokines, cytokine receptors, and toll‐like receptors dictates pathophysiology of COVID‐19 disease
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DOI: 10.1002/jmv.27849
Abstract: Innate and acquired immunity responses are crucial for viral infection elimination. However, genetic variations in coding genes may exacerbate the inflammation or initiate devastating cytokine storms which poses severe respiratory conditions in coronavirus disease‐19 (COVID‐19).… read more here.
Keywords: toll like; cytokine receptors; cytokines cytokine; proinflammatory cytokines ... See more keywords
Proinflammatory cytokines levels in patients with temporomandibular joint disorder undergoing arthroscopy
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DOI: 10.1007/s10006-021-01014-1
Abstract: Biomarkers represent objective indicators of normal processes, pathology, or responses to therapeutic intervention. The purpose of this study is to evaluate the levels of proinflammatory cytokines in synovial fluid of the temporomandibular joint (TMJ) and… read more here.
Keywords: levels patients; proinflammatory cytokines; disorder; temporomandibular joint ... See more keywords
Platelet-rich plasma and/or sildenafil topical applications accelerate and better repair wound healing in rats through regulation of proinflammatory cytokines and collagen/TGF-β1 pathway
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DOI: 10.1007/s11356-020-10042-5
Abstract: Platelet-rich plasma (PRP) composites of various cytokines and growth factors which have the potential to activate and speed the process of wound repair. Sildenafil also is a potent stimulator of angiogenesis which favors its potential… read more here.
Keywords: collagen; wound healing; prp sch; proinflammatory cytokines ... See more keywords
Increased testosterone and proinflammatory cytokines in patients with polycystic ovary syndrome correlate with elevated GnRH receptor autoantibody activity assessed by a fluorescence resonance energy transfer-based bioassay
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DOI: 10.1007/s12020-021-02761-7
Abstract: The recently identified agonistic autoantibodies (AAb) to the gonadotropin-releasing hormone receptor (GnRHR) are a novel investigative and therapeutic target for polycystic ovary syndrome (PCOS). In this study, we used a new cell-based fluorescence resonance energy… read more here.
Keywords: testosterone proinflammatory; proinflammatory cytokines; activity; gnrhr aab ... See more keywords
Korean Red Ginseng improves atopic dermatitis-like skin lesions by suppressing expression of proinflammatory cytokines and chemokines in vivo and in vitro
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DOI: 10.1016/j.jgr.2016.02.003
Abstract: Background The prevalence of allergic inflammatory diseases such as atopic dermatitis (AD), asthma, and allergic rhinitis worldwide has increased and complete recovery is difficult. Korean Red Ginseng, which is the heat-processed root of Panax ginseng… read more here.
Keywords: ginseng; proinflammatory cytokines; red ginseng; expression proinflammatory ... See more keywords
Melatonin mitigates thioacetamide‐induced hepatic fibrosis via antioxidant activity and modulation of proinflammatory cytokines and fibrogenic genes
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DOI: 10.1016/j.lfs.2017.11.036
Abstract: Aims: The potential antifibrotic effects of melatonin against induced hepatic fibrosis were explored. Main methods: Rats were allocated into four groups: placebo; thioacetamide (TAA) (200 mg/kg bwt, i.p twice weekly for two months); melatonin (5… read more here.
Keywords: proinflammatory; proinflammatory cytokines; fibrogenic genes; hepatic fibrosis ... See more keywords
The pathophysiology of SARS-CoV-2: A suggested model and therapeutic approach
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DOI: 10.1016/j.lfs.2020.118166
Abstract: Abstract In this paper, a model is proposed of the pathophysiological processes of COVID-19 starting from the infection of human type II alveolar epithelial cells (pneumocytes) by SARS-CoV-2 and culminating in the development of ARDS.… read more here.
Keywords: proinflammatory cytokines; cov suggested; pathophysiology sars; model ... See more keywords
Inflammation, cognitive dysfunction, and suicidal ideation among patients with major depression.
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DOI: 10.1017/s1092852921000729
Abstract: Dysregulated proinflammatory cytokines have been shown to be associated with suicidal behavior. Cognitive deficits in working memory and inhibitory control have been demonstrated in depressed patients and people with suicidal ideation (SI). However, the association… read more here.
Keywords: among patients; proinflammatory cytokines; patients major; suicidal ideation ... See more keywords