Streptococcal sagA activates a proinflammatory response in mast cells by a sublytic mechanism
Sign Up to like & getrecommendations! Published in 2019 at "Cellular Microbiology"
DOI: 10.1111/cmi.13064
Abstract: Mast cells are implicated in the innate proinflammatory immune defence against bacterial insult, but the mechanisms through which mast cells respond to bacterial encounter are poorly defined. Here, we addressed this issue and show that… read more here.
Keywords: proinflammatory response; mast cells; mast; saga ... See more keywords
Diverse proinflammatory response in pharyngeal epithelial cells upon interaction with Neisseria meningitidis carriage and invasive isolates
Sign Up to like & getrecommendations! Published in 2024 at "BMC Infectious Diseases"
DOI: 10.1186/s12879-024-09186-3
Abstract: Background Invasive meningococcal disease (IMD), including sepsis and meningitis, can develop when Neisseria meningitidis bacteria breach the barrier and gain access to the circulation. While IMD is a rare outcome of bacterial exposure, colonization of… read more here.
Keywords: response pharyngeal; response; neisseria meningitidis; carriage ... See more keywords
TIM4+macrophages suppress the proinflammatory response to maintain the chronic alveolar echinococcosis infection
Sign Up to like & getrecommendations! Published in 2025 at "Frontiers in Cellular and Infection Microbiology"
DOI: 10.3389/fcimb.2025.1600686
Abstract: Background Alveolar echinococcosis (AE), a severe zoonotic disease predominantly endemic to pastoral regions, is characterized by hepatic parasitic lesions caused by Echinococcus multilocularis. Methods This study investigated the role of T-cell immunoglobulin and mucin domain-4… read more here.
Keywords: alveolar echinococcosis; maintain; infection; tim ... See more keywords
Mycobacterium bovis naturally infected calves present a higher bacterial load and proinflammatory response than adult cattle
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Veterinary Science"
DOI: 10.3389/fvets.2023.1105716
Abstract: Granulomas are characteristic bovine tuberculosis lesions; studying this structure has improved our understanding of tuberculosis pathogenesis. However, the immune response that develops in granulomas of young cattle naturally infected with Mycobacterium bovis (M. bovis) has… read more here.
Keywords: bovis; naturally infected; proinflammatory response; mycobacterium bovis ... See more keywords