A role for PFKFB3/iPFK2 in metformin suppression of adipocyte inflammatory responses.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of molecular endocrinology"
DOI: 10.1530/jme-17-0066
Abstract: Metformin improves obesity-associated metabolic dysregulation, but has controversial effects on adipose tissue inflammation. The objective of the study is to examine the direct effect of metformin on adipocyte inflammatory responses and elucidate the underlying mechanisms.… read more here.
Keywords: inflammatory responses; adipocyte inflammatory; metformin; pfkfb3 ipfk2 ... See more keywords
YAP9/A20 complex suppresses proinflammatory responses and provides novel anti-inflammatory therapeutic potentials
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.914381
Abstract: Innate anti-inflammatory mechanisms are essential for immune homeostasis and can present opportunities to intervene inflammatory diseases. In this report, we found that YAP isoform 9 (YAP9) is an essential negative regulator of the potent inflammatory… read more here.
Keywords: yap9 a20; proinflammatory responses; novel anti; anti inflammatory ... See more keywords
Activation of Early Proinflammatory Responses by TBEV NS1 Varies between the Strains of Various Subtypes
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24021011
Abstract: Tick-borne encephalitis (TBE) is an emerging zoonosis that may cause long-term neurological sequelae or even death. Thus, there is a growing interest in understanding the factors of TBE pathogenesis. Viral genetic determinants may greatly affect… read more here.
Keywords: early proinflammatory; responses tbev; proinflammatory responses; activation early ... See more keywords
Time-Dependent Proinflammatory Responses Shape Virus Interference during Coinfections of Influenza A Virus and Influenza D Virus
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DOI: 10.3390/v14020224
Abstract: Both influenza A virus (IAV) and influenza D virus (IDV) are enzootic in pigs. IAV causes approximately 100% morbidity with low mortality, whereas IDV leads to only mild respiratory diseases in pigs. In this study,… read more here.
Keywords: iav; proinflammatory responses; interference; idv ... See more keywords
Proinflammatory Responses in SARS-CoV-2 and Soluble Spike Glycoprotein S1 Subunit Activated Human Macrophages
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DOI: 10.3390/v15030754
Abstract: Critically ill COVID-19 patients display signs of generalized hyperinflammation. Macrophages trigger inflammation to eliminate pathogens and repair tissue, but this process can also lead to hyperinflammation and resulting exaggerated disease. The role of macrophages in… read more here.
Keywords: proinflammatory responses; cov soluble; subunit; pro inflammatory ... See more keywords