Amino acid polymorphisms in human histocompatibility leukocyte antigen class II and proinsulin epitope have impacts on type 1 diabetes mellitus induced by immune-checkpoint inhibitors
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DOI: 10.3389/fimmu.2023.1165004
Abstract: Introduction Immune-checkpoint inhibitors are effective in various advanced cancers. Type 1 diabetes mellitus induced by them (ICI-T1DM) is a serious complication requiring prompt insulin treatment, but the immunological mechanism behind it is unclear. Methods We… read more here.
Keywords: acid polymorphisms; ici t1dm; proinsulin epitope; amino acid ... See more keywords