The distribution of Cdh20 mRNA demarcates somatotopic subregions and subpopulations of spiny projection neurons in the rat dorsolateral striatum
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Comparative Neurology"
DOI: 10.1002/cne.25215
Abstract: The dorsolateral striatum (DLS) of rodents is functionally subdivided into somatotopic subregions that represent each body part along both the dorsoventral and anteroposterior (A‐P) axes and play crucial roles in sensorimotor functions via corticostriatal pathways.… read more here.
Keywords: dls; projection neurons; dorsolateral striatum; spiny projection ... See more keywords
Mammalian Target of Rapamycin-RhoA Signaling Impairments in Direct Striatal Projection Neurons Induce Altered Behaviors and Striatal Physiology in Mice
Sign Up to like & getrecommendations! Published in 2020 at "Biological Psychiatry"
DOI: 10.1016/j.biopsych.2020.05.029
Abstract: BACKGROUND As an integrator of molecular pathways, mTOR (mammalian target of rapamycin) has been associated with diseases including neurodevelopmental, psychiatric, and neurodegenerative disorders such as autism spectrum disorder, schizophrenia, and Huntington's disease. An important brain… read more here.
Keywords: striatal projection; striatal physiology; projection neurons; physiology ... See more keywords
Visual Projection Neurons Mediating Directed Courtship in Drosophila
Sign Up to like & getrecommendations! Published in 2018 at "Cell"
DOI: 10.1016/j.cell.2018.06.020
Abstract: Many animals rely on vision to detect, locate, and track moving objects. In Drosophila courtship, males primarily use visual cues to orient toward and follow females and to select the ipsilateral wing for courtship song.… read more here.
Keywords: projection neurons; courtship; visual projection; lc10 neurons ... See more keywords
Reconstruction of 1,000 Projection Neurons Reveals New Cell Types and Organization of Long-Range Connectivity in the Mouse Brain
Sign Up to like & getrecommendations! Published in 2019 at "Cell"
DOI: 10.1016/j.cell.2019.07.042
Abstract: Neuronal cell types are the nodes of neural circuits that determine the flow of information within the brain. Neuronal morphology, especially the shape of the axonal arbor, provides an essential descriptor of cell type and… read more here.
Keywords: cell types; brain; mouse brain; projection neurons ... See more keywords
Activity in projection neurons from prelimbic cortex to the PVT is necessary for retrieval of morphine withdrawal memory.
Sign Up to like & getrecommendations! Published in 2021 at "Cell reports"
DOI: 10.1016/j.celrep.2021.108958
Abstract: Previous work has shown that the paraventricular nucleus of the thalamus (PVT) is an important region that is involved in the conditioned context-induced retrieval of morphine withdrawal memory. However, the upstream neural circuits that activate… read more here.
Keywords: pvt; withdrawal memory; morphine withdrawal; retrieval morphine ... See more keywords
Huntingtin-Mediated Multipolar-Bipolar Transition of Newborn Cortical Neurons Is Critical for Their Postnatal Neuronal Morphology
Sign Up to like & getrecommendations! Published in 2017 at "Neuron"
DOI: 10.1016/j.neuron.2016.11.035
Abstract: In the developing cortex, projection neurons undergo multipolar-bipolar transition, radial-directed migration, and maturation. The contribution of these developmental steps to the structure of the adult cortex is not completely understood. Here, we report that huntingtin… read more here.
Keywords: htt; multipolar bipolar; projection neurons; neuronal morphology ... See more keywords
Epigenomic diversity of cortical projection neurons in the mouse brain
Sign Up to like & getrecommendations! Published in 2021 at "Nature"
DOI: 10.1038/s41586-021-03223-w
Abstract: Neuronal cell types are classically defined by their molecular properties, anatomy and functions. Although recent advances in single-cell genomics have led to high-resolution molecular characterization of cell type diversity in the brain1, neuronal cell types… read more here.
Keywords: cortico cortical; diversity; projection neurons; projection ... See more keywords
GABAergic neurons in the olfactory cortex projecting to the lateral hypothalamus in mice
Sign Up to like & getrecommendations! Published in 2019 at "Scientific Reports"
DOI: 10.1038/s41598-019-43580-1
Abstract: Olfaction guides goal-directed behaviours including feeding. To investigate how central olfactory neural circuits control feeding behaviour in mice, we performed retrograde tracing from the lateral hypothalamus (LH), an important feeding centre. We observed a cluster… read more here.
Keywords: olfactory cortex; projection neurons; neurons olfactory; mice ... See more keywords
Neuronal architecture of the second-order CO2 pathway in the brain of a noctuid moth
Sign Up to like & getrecommendations! Published in 2020 at "Scientific Reports"
DOI: 10.1038/s41598-020-76918-1
Abstract: Many insects possess the ability to detect fine fluctuations in the environmental CO2 concentration. In herbivorous species, plant-emitted CO2, in combination with other sensory cues, affect many behaviors including foraging and oviposition. In contrast to… read more here.
Keywords: insects; order; noctuid moth; projection neurons ... See more keywords
An evolutionarily acquired microRNA shapes development of mammalian cortical projections
Sign Up to like & getrecommendations! Published in 2020 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2006700117
Abstract: Significance The mammalian central nervous system contains unique projections from the cerebral cortex thought to underpin complex motor and cognitive skills, including the corticospinal tract and corpus callosum. The neurons giving rise to these projections—corticospinal… read more here.
Keywords: corticospinal tract; evolutionarily acquired; corpus callosum; projection neurons ... See more keywords
Mild Traumatic Brain Injury Reduces Spine Density of Projection Neurons in the Medial Prefrontal Cortex and Impairs Extinction of Contextual Fear Memory.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of neurotrauma"
DOI: 10.1089/neu.2016.4898
Abstract: Epidemiology studies have found that a comorbidity exists between traumatic brain injury (TBI) and stress-related disorders. However, the anatomical and cellular bases for this association is poorly understood. An inability to extinguish the memory of… read more here.
Keywords: cortex; spine density; projection neurons; injury ... See more keywords