Functionalized C-nucleosides as remarkable RNA binders: targeting of prokaryotic ribosomal A-site RNA.
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DOI: 10.1039/c9cc04915k
Abstract: RNA represents an extremely promising and yet challenging therapeutic target. Here, we report the design of a series of C-nucleosides as original RNA binders. Some of them bind strongly and selectively to A-site prokaryotic ribosomal… read more here.
Keywords: rna; functionalized nucleosides; site; rna binders ... See more keywords