Prokineticin receptors interact unselectively with several G protein subtypes but bind selectively to β-arrestin 2.
Sign Up to like & getrecommendations! Published in 2021 at "Cellular signalling"
DOI: 10.1016/j.cellsig.2021.110000
Abstract: Prokineticin 1 (pk1) and prokineticin 2 (pk2) interact with two structurally related G-protein coupled receptors, prokineticin receptor 1 (PKR1) and prokineticin receptor 2 (PKR2). Cellular signalling studies show that the activated receptors can evoke Ca2+-mobilization,… read more here.
Keywords: protein subtypes; prokineticin receptors; receptor; prokineticin ... See more keywords
Non-Peptide Agonists and Antagonists of the Prokineticin Receptors
Sign Up to like & getrecommendations! Published in 2022 at "Current Issues in Molecular Biology"
DOI: 10.3390/cimb44120431
Abstract: The prokineticin family comprises a group of secreted peptides that can be classified as chemokines based on their structural features and chemotactic and immunomodulatory functions. Prokineticins (PKs) bind with high affinity to two G protein-coupled… read more here.
Keywords: system; prokineticin receptors; agonists antagonists; antagonists prokineticin ... See more keywords