Regulatory role of melatonin and BMP-4 in prolactin production by rat pituitary lactotrope GH3 cells
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DOI: 10.1016/j.peptides.2017.06.001
Abstract: HIGHLIGHTSMelatonin receptor activation suppresses PRL expression and secretion by lactotrope GH3 cells.MT2 activation regulates PRL level by suppressing cAMP, BMP‐Smad and ERK pathways.BMP‐4 induces PRL expression but also upregulates MT2 as a possible feedback loop.… read more here.
Keywords: melatonin; prolactin production; bmp; gh3 cells ... See more keywords