Prolidase is a critical enzyme for complete gliadin digestion in Tenebrio molitor larvae.
Sign Up to like & getrecommendations! Published in 2017 at "Archives of insect biochemistry and physiology"
DOI: 10.1002/arch.21395
Abstract: Prolidase is a proline-specific metallopeptidase that cleaves imidodipeptides with C-terminal Pro residue. Prolidase was purified and characterized from the Tenebrio molitor larval midgut. The enzyme was localized in the soluble fraction of posterior midgut tissues,… read more here.
Keywords: prolidase critical; prolidase; tenebrio molitor; molitor ... See more keywords
Increased prolidase activity in Alzheimer's dementia: A case-control study.
Sign Up to like & getrecommendations! Published in 2020 at "Asian journal of psychiatry"
DOI: 10.1016/j.ajp.2020.102242
Abstract: Prolidase enzyme, which catalyzes the final step in collagen metabolism can influence the cognitive functions through changes in extracellular matrix (ECM) resulting in altered synaptic connectivity in Alzheimer's disease (AD). In this study, it was… read more here.
Keywords: prolidase; prolidase activity; control; study ... See more keywords
Obstinate leg ulceration secondary to prolidase deficiency, treated with 5% topical proline
Sign Up to like & getrecommendations! Published in 2022 at "Clinical and Experimental Dermatology"
DOI: 10.1111/ced.15085
Abstract: Prolidase deficiency is a rare cause of chronic ulceration with less than 100 reported cases in the literature. This article highlights to clinicians the features of this uncommon genodermatosis, the challenge of diagnosis, and treatment… read more here.
Keywords: prolidase deficiency; leg ulceration; obstinate leg; prolidase ... See more keywords
A rare cause of cutaneous ulceration: Prolidase deficiency
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DOI: 10.1111/iwj.13138
Abstract: Dear Editors, Prolidase deficiency (PD) is a rare hereditary disease characterised by skin lesions including ulcerations, frequent infections, characteristic facies, mental retardation, and splenomegaly. Diagnosis of prolidase activity is made by sequence analysis of the… read more here.
Keywords: pepd gene; prolidase deficiency; prolidase; ulceration ... See more keywords
Prolidase Stimulates Proliferation and Migration through Activation of the PI3K/Akt/mTOR Signaling Pathway in Human Keratinocytes
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DOI: 10.3390/ijms21239243
Abstract: Recent reports have indicated prolidase (PEPD) as a ligand of the epidermal growth factor receptor (EGFR). Since this receptor is involved in the promotion of cell proliferation, growth, and migration, we aimed to investigate whether… read more here.
Keywords: proliferation migration; prolidase; pi3k akt; migration ... See more keywords